Liver-Spleen Ratio: Can It Be Used for the Prediction of Coronary Artery Disease?

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dc.contributor.authorPoyraz, Necdet
dc.contributor.authorOzer, Hakan
dc.contributor.authorBaloglu, Ismail
dc.contributor.authorKadiyoran, Cengiz
dc.contributor.authorYilmaz, Pinar Diydem
dc.contributor.authorSertdemir, Ahmet Lutfu
dc.contributor.authorTurkmen, Kultigin
dc.date.accessioned2024-02-23T14:41:02Z
dc.date.available2024-02-23T14:41:02Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractBackground: Considering that ectopic fat accumulation in various organs, especially the heart and liver, is a cardiometabolic risk factor, the need for easily accessible markers of ectopic fat accumulation is inevitable. The main starting point of the study is based on the hypothesis of predicting cardiovascular disease risk through the link that can be established between the liver-spleen ratio, which is one of the strong indicators of hepatosteatosis, and epicardial adipose tissue volume. Methods: This was a retrospective study. The records of 283 consecutive patients who underwent coronary computed tomography angiography in our Radiology Department were reviewed retrospectively from our hospital's system. All patients' epicardial adipose tissue volume and liver-spleen ratio were calculated using appropriate criteria on non-contrast computed tomography images. Additionally, the Coronary Artery Disease-Reporting and Data System was calculated on contrast computed tomography images. The participating patients were divided into groups according to the liver-spleen ratio and Coronary Artery Disease-Reporting and Data System score. Results: We found that while there was a negative correlation between the liver-spleen ratio and epicardial adipose tissue volume in the hepatosteatosis group, this relationship was not observed in the non-steatosis group. In addition, we observed that the family history of cardiovascular disease and the frequency of cardiovascular disease were higher in the hepatosteatosis group than in the other group, and there was a correlation between cardiovascular disease and the liver-spleen ratio. Also, we found that age and liver- spleen ratio values were found to be independent predictors of coronary artery disease. Conclusion: In our study, we found that the frequency of cardiovascular disease was lower in patients with a high liver-spleen ratio. We also demonstrated in the study that the liver-spleen ratio, which indicates a low level of epicardial adipose tissue volume accumulation, is an independent predictor of cardiovascular disease. In addition, the use of liver-spleen ratio, which is more valuable than liver attenuation in predicting hepatic steatosis, may be more useful in evaluating the risk of hepatosteatosis-related cardiovascular disease.en_US
dc.identifier.doi10.5152/AnatolJCardiol.2022.1787
dc.identifier.endpage770en_US
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue10en_US
dc.identifier.pmid35943316en_US
dc.identifier.scopus2-s2.0-85139554968en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage762en_US
dc.identifier.urihttps://doi.org/10.5152/AnatolJCardiol.2022.1787
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16677
dc.identifier.volume26en_US
dc.identifier.wosWOS:000882552600005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofAnatolian Journal Of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLiver-Spleen Ratioen_US
dc.subjectHepatosteatosisen_US
dc.subjectEpicardial Adipose Tissueen_US
dc.subjectCardiovascular Diseaseen_US
dc.titleLiver-Spleen Ratio: Can It Be Used for the Prediction of Coronary Artery Disease?en_US
dc.typeArticleen_US

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