Monitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environment

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dc.contributor.authorAydin, Senar
dc.contributor.authorAydin, Mehmet Emin
dc.contributor.authorUlvi, Arzu
dc.date.accessioned2024-02-23T13:59:32Z
dc.date.available2024-02-23T13:59:32Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractThe occurrence of anti-inflammatory and analgesic pharmaceuticals (AIAPs) in the effluents of 16 hospitals, influent and effluent of wastewater treatment plant (WWTP), the contribution and mass load of each hospital to WWTP influent, and the removal efficiencies in WWTP were investigated. Environmental risk was also evaluated by toxicity tests using organisms from three different trophic levels. Acetaminophen had the highest concentration in summer and winter samples, followed by ketoprofen, ibuprofen, and naproxen. The total daily load of AIAPs detected in influent of WWTP was 1677 mg/day/1000 inhabitants in summer and 5074 mg/day/1000 inhabitants in winter. The contribution of 16 hospitals to the total AIAP load in influent of WWTP was 11.30% in summer and 7.09% in winter. The highest mass loads were calculated as 203 mg/bed.day in general hospital in summer and 300 mg/bed.day in pediatric hospital in winter. The removal efficiencies of AIAPs in WWTP ranged between 13% and 100% in summer and 0.88% and 99% in winter. WWTP is not sufficient to remove all the AIAPs. Diclofenac (in summer), mefenamic acid, indomethacin, and phenylbutazone exhibited poor removal below 50%. The effluents of the WWTP exhibited a low risk for fish and Daphnia magna and an insignificant risk for algae.en_US
dc.description.sponsorshipTurkish Academia of Sciences Awards for Outstanding Young Scientists (TUBA-GEBIP)en_US
dc.description.sponsorshipThis work was supported by Turkish Academia of Sciences Awards for Outstanding Young Scientists (TUBA-GEBIP).en_US
dc.identifier.doi10.1007/s11356-019-06821-4
dc.identifier.endpage36902en_US
dc.identifier.issn0944-1344
dc.identifier.issn1614-7499
dc.identifier.issue36en_US
dc.identifier.pmid31745804en_US
dc.identifier.scopus2-s2.0-85075373132en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage36887en_US
dc.identifier.urihttps://doi.org/10.1007/s11356-019-06821-4
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11234
dc.identifier.volume26en_US
dc.identifier.wosWOS:000507283600067en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofEnvironmental Science And Pollution Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnalgesicsen_US
dc.subjectAnti-Inflammatoriesen_US
dc.subjectEnvironmental Risken_US
dc.subjectHospital Effluentsen_US
dc.subjectWastewater Treatment Planten_US
dc.titleMonitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environmenten_US
dc.typeArticleen_US

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