Total antioxidant, total oxidant and serum paraoxonase levels according to lipid administration method in parenterally fed premature infants

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dc.contributor.authorKonak, Murat
dc.contributor.authorTarakci, Nuriye
dc.contributor.authorAltunhan, Huseyin
dc.contributor.authorAnnagur, Ali
dc.contributor.authorToker, Aysun
dc.contributor.authorOrs, Rahmi
dc.date.accessioned2024-02-23T14:20:36Z
dc.date.available2024-02-23T14:20:36Z
dc.date.issued2017
dc.departmentNEÜen_US
dc.description.abstractObjective: The aim of our study was to determine whether lipid solutions delivered separately or in mixture with total parenteral nutrition (TPN) solutions effect the balance between oxidant and antioxidant levels in premature infants.Methods: A total of 60 preterm newborns who were delivered at their 30-34 gestational weeks and received TPN were included in the study. Premature newborns were randomized into two groups based on the delivery method of the lipid solution, separately (Group 1) or in mixture with TPN solutions (Group 2). Total antioxidant status (TAS), total oxidant status (TOS) and paraoxonase (PON-1) levels were analyzed in both blood samples, and oxidative stress index (OSI) was also calculated.Results: Thirty cases from both groups were included in the study. Statistically significant decrease in the level of TAS and increase in the level of PON-1 were detected at 72h of TPN therapy in both groups (p<0.05). Statistically significant decrease in both TOS and OSI levels were observed in Group 2 (p<0.05). In association with these findings, any statistically significant intergroup difference was not detected in both parameters regarding oxidant balance (p>0.05).Conclusion: Our study showed that according to lipid administration method any difference for oxidant-antioxidant balance was not detected.en_US
dc.identifier.doi10.1080/14767058.2016.1224231
dc.identifier.endpage1738en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue14en_US
dc.identifier.pmid27583439en_US
dc.identifier.scopus2-s2.0-84984691669en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1734en_US
dc.identifier.urihttps://doi.org/10.1080/14767058.2016.1224231
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13231
dc.identifier.volume30en_US
dc.identifier.wosWOS:000401487100019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPrematureen_US
dc.subjectParenteral Nutritionen_US
dc.subjectLipid Methoden_US
dc.subjectOxidant Statusen_US
dc.titleTotal antioxidant, total oxidant and serum paraoxonase levels according to lipid administration method in parenterally fed premature infantsen_US
dc.typeArticleen_US

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