Evaluation of the Effectiveness of Liquid Platelet-Rich Fibrin and Deproteinized Bovine Bone Mineral Mixture on Newly Formed Bone in Maxillary Sinus Augmentation: A Split-Mouth, Histomorphometric Study

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dc.contributor.authorIrdem, H. O.
dc.contributor.authorDolanmaz, D.
dc.contributor.authorEsen, A.
dc.contributor.authorUnlukal, N.
dc.contributor.authorSimsek, S.
dc.date.accessioned2024-02-23T14:37:55Z
dc.date.available2024-02-23T14:37:55Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractObjective: We aimed to investigate the effectiveness of the liquid PRF-DBBM mixture on new bone formation in maxillary sinus augmentation. Material and Methods: Seven patients requiring two-stage bilateral maxillary sinus augmentation were included in the study. The patients were selected according to the criteria of having an alveolar bone height of at least 2 mm in the atrophic region. The elevated sinus cavities were randomly grafted with DBBM + liquid PRF (test) or DBBM alone (control) in a split-mouth design. Bone samples were collected during implant surgery with a trephine bur for histomorphometric evaluation after 4 months. Results: In the control group, the newly formed bone was 39.49%, the mature bone was 15.66%, the residual graft was 15.62%, and the fibrous tissue ratio 28.59%, while in the test group, the newly formed bone (NFB) was 45.95%, the mature bone was 14.40%, the residual graft was 10.32%, and the fibrous tissue was 29.31%. No statistically significant difference was found between the groups in terms of the parameters studied (p > 0.05). The mean osteocalcin score in the control group was 2.70 +/- 0.39, while it was 2.81 +/- 0.36 in the test group. There was no statistically significant difference between the averages of osteocalcin scores of the groups (p > 0.05). Conclusion: The results of our study showed that DBBM is a reliable graft material for maxillary sinus augmentation even in the early period. Combining of DBBM with liquid-PRF contributed to new bone formation over a four-month period, but this contribution was not statistically significant.en_US
dc.description.sponsorshipSelcuk University [15102043]en_US
dc.description.sponsorshipThis study was supported by the Selcuk University Scientific Research Projects Coordinatorship [grant numbers 15102043]en_US
dc.identifier.doi10.4103/njcp.njcp_692_20
dc.identifier.endpage1372en_US
dc.identifier.issn1119-3077
dc.identifier.issue9en_US
dc.identifier.pmid34531351en_US
dc.identifier.scopus2-s2.0-85115845168en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1366en_US
dc.identifier.urihttps://doi.org/10.4103/njcp.njcp_692_20
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16279
dc.identifier.volume24en_US
dc.identifier.wosWOS:000751358000017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofNigerian Journal Of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBone Graftsen_US
dc.subjectBone Regenerationen_US
dc.subjectHistomorphometryen_US
dc.subjectPlatelet-Rich Fibrinen_US
dc.subjectSinus Liften_US
dc.titleEvaluation of the Effectiveness of Liquid Platelet-Rich Fibrin and Deproteinized Bovine Bone Mineral Mixture on Newly Formed Bone in Maxillary Sinus Augmentation: A Split-Mouth, Histomorphometric Studyen_US
dc.typeArticleen_US

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