Hypomagnesemia Among Outpatient Long-Term Proton Pump Inhibitor Users

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dc.contributor.authorBiyik, Murat
dc.contributor.authorSolak, Yalcin
dc.contributor.authorUcar, Ramazan
dc.contributor.authorCifci, Sami
dc.contributor.authorTekis, Dilek
dc.contributor.authorPolat, Ilker
dc.contributor.authorGoktepe, Mevluet Hakan
dc.date.accessioned2024-02-23T14:21:14Z
dc.date.available2024-02-23T14:21:14Z
dc.date.issued2017
dc.departmentNEÜen_US
dc.description.abstractProton pump inhibitors (PPIs) are extensively prescribed drugs usually used for a long period. Recent reports linked PPI use with development of hypomagnesemia. However, there is still uncertainty regarding risk of hypomagnesemia in outpatients who were on long-term PPI use. Thus, we aimed to evaluate frequency of hypomagnesemia among a well-defined outpatient patient cohort with no other possible risk factors affecting serum magnesium levels. This was a case-control study carried out at the outpatient gastroenterology clinic of a University hospital. Patients who were on PPI therapy for at least 6 months without diuretic use and chronic kidney disease were included. Patients who were subjected to the same inclusion and exclusion criteria and not using PPI were included as control subjects. One hundred fifty-four patients and 84 control subjects were included. The mean duration of PPI use was 27.5 +/- 2.5 months. Mean serum magnesium levels of PPI users and nonusers were 2.17 +/- 0.20 mg/dL and 2.19 +/- 0.15 mg/dL, respectively. None of the patient had a serum magnesium level below laboratory lower range of 1.7 mg/dL. Our results showed that for typical gastroenterology outpatient clinic patients with no other risk factors affecting serum magnesium levels, long-term PPI use did not affect serum magnesium levels.en_US
dc.identifier.doi10.1097/MJT.0000000000000154
dc.identifier.endpageE55en_US
dc.identifier.issn1075-2765
dc.identifier.issn1536-3686
dc.identifier.issue1en_US
dc.identifier.pmid25353358en_US
dc.identifier.scopus2-s2.0-85009802378en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpageE52en_US
dc.identifier.urihttps://doi.org/10.1097/MJT.0000000000000154
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13513
dc.identifier.volume24en_US
dc.identifier.wosWOS:000393873700008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofAmerican Journal Of Therapeuticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHypomagnesemiaen_US
dc.subjectProton Pomp Inhibitorsen_US
dc.titleHypomagnesemia Among Outpatient Long-Term Proton Pump Inhibitor Usersen_US
dc.typeArticleen_US

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