Is Retrograde Intrarenal Surgery as Safe for Children as It Is for Adults?

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dc.contributor.authorOzkent, Mehmet Serkan
dc.contributor.authorPiskin, Mehmet Mesut
dc.contributor.authorBalasar, Mehmet
dc.contributor.authorGoger, Yunus Emre
dc.contributor.authorSonmez, Mehmet Giray
dc.date.accessioned2024-02-23T14:26:41Z
dc.date.available2024-02-23T14:26:41Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractIntroduction: The primary aim of this study is to compare the efficacy and safety of retrograde intrarenal surgery (RIRS) among the children and adults with similar stone burdens and locations. Also, the secondary aim of this study is to identify the factors affecting the stone-free rates (SFRs) of RIRS. Methods: We retrospectively compared perioperative results, SFRs, and complication rates (CRs) between pediatric (group 1, n: 55) and adult (group 2, n: 220) age groups diagnosed with kidney stones and treated by flexible ureterorenoscopy using the same instruments. Furthermore, multivariate analysis was performed to determine the factors affecting the SFR. Results: A total of 275 patients (pediatric group: 55; adult group: 220) were included in this study. The mean age of pediatric and adult groups was 7.2 +/- 5.3 and 43.9 +/- 15.1, respectively. The mean stone size was 13.9 +/- 6.6 mm in the pediatric group compared to 14.8 +/- 6.7 mm in the adult group (p = 0.35). Stone localizations and number were similar. JJ stenting for passive dilatation and use of UAS were higher in the pediatric group (p = 0.002; p = 0.017). However, postoperative double pigtail stenting rate was higher in the adult group (p < 0.001). Total CR was 13.8% and mostly Clavien I-II, and no difference was observed between the 2 groups (p = 0.541). The SFRs between the groups were similar (pediatric group: 81.8%; adult group: 78.2%; p = 0.554). On multivariate analysis, stone size (p < 0.001) and lower calyx stone (p < 0.001) were the negative predictive factors for SFR. Conclusion: There are small technical differences between pediatric patients and adult patients in our study, but RIRS in children is as safe and efficient as it is in adults.en_US
dc.identifier.doi10.1159/000517290
dc.identifier.endpage1045en_US
dc.identifier.issn0042-1138
dc.identifier.issn1423-0399
dc.identifier.issue11.Araen_US
dc.identifier.pmid34247163en_US
dc.identifier.scopus2-s2.0-85111708394en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1039en_US
dc.identifier.urihttps://doi.org/10.1159/000517290
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14288
dc.identifier.volume105en_US
dc.identifier.wosWOS:000673937000001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofUrologia Internationalisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndourologyen_US
dc.subjectNephrolithiasisen_US
dc.subjectRetrograde Intrarenal Surgeryen_US
dc.subjectUrolithiasisen_US
dc.subjectStone Diseaseen_US
dc.titleIs Retrograde Intrarenal Surgery as Safe for Children as It Is for Adults?en_US
dc.typeArticleen_US

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