Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study

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dc.contributor.authorEroglu, Cennet-Neslihan
dc.contributor.authorDurmus, Ercan
dc.contributor.authorKiresi, Demet
dc.date.accessioned2024-02-23T14:38:24Z
dc.date.available2024-02-23T14:38:24Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractObjectives: The aim of the present study was to investigate the analgesic and anti-inflammatory effects of dexketoprofen trometamol (DT) and paracetamol on deep acute somatic pain and inflammation in patients undergoing impacted third molar surgery. This study was planned to present benefits that we could obtain with low burden of drug. Study Design: Effects of drugs, which were administered preemptively before the procedure, on pain, mouth-opening limitation, and swelling were assessed by visual analogue scale (VAS), magnetic resonance imaging (MRI), and mouth-opening measurement. Following surgery, time intervals when the patients first need to receive the drug were measured. Results: The VAS scores of the patients were lower in the side treated with DT than that in the paracetamol treated side. There was no significant difference between the groups in terms of mouth-opening limitation. MRI recordings revealed that swelling was lower in the side treated with paracetamol than DT treated side. Conclusions: Administration of the drugs before surgery contributed to the postoperative patient comfort. The analgesic activity of 12.5 mg dose of DT was similar to, even better than, the analgesic activity of 500 mg dose of paracetamol; however, DT had insufficient anti-inflammatory efficacy.en_US
dc.identifier.doi10.4317/medoral.19835
dc.identifier.endpageE627en_US
dc.identifier.issn1698-6946
dc.identifier.issue6en_US
dc.identifier.pmid25129247en_US
dc.identifier.scopus2-s2.0-84908410393en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpageE622en_US
dc.identifier.urihttps://doi.org/10.4317/medoral.19835
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16515
dc.identifier.volume19en_US
dc.identifier.wosWOS:000345372800015en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMedicina Oral S Len_US
dc.relation.ispartofMedicina Oral Patologia Oral Y Cirugia Bucalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDexketoprofen Trometamolen_US
dc.subjectParacetamolen_US
dc.subjectMagnetic Resonance Imagingen_US
dc.titleEffect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot studyen_US
dc.typeArticleen_US

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