Case-based review of dietary management of cystinuria

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dc.contributor.authorUcmak, Harun
dc.contributor.authorSonmez, Mehmet Giray
dc.contributor.authorGuven, Selcuk
dc.date.accessioned2024-02-23T13:43:44Z
dc.date.available2024-02-23T13:43:44Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractPurpose The currently recommended treatment strategy for cystine stone formers is based on a progressive approach that starts with the most conservative measures. In patients with cystinuria, increased patient compliance with dietary management and medical treatment is associated with fewer stone interventions. In this case-based review, the dietary management of cystine stone former was reviewed under the guidance of evidence-based medicine. Methods The dietary management of the 13-year-old cystinuria patient, who underwent 18 endourological stone interventions, was reviewed in the light of evidence-based medicine. A literature search was performed in Pubmed, MEDLINE, Embase, and Cochrane Library databases according to PRISMA guidelines published from 1993 to September 2022. A total of 304 articles were included in this paper. Results In managing patients with cystinuria, hyperhydration, and alkalinization of the urine with medical treatment, the rational use of cystine-binding drugs by taking into account individual situations has come to the fore. A limited study has argued that a vegetarian diet is effective as the alkaline load from fruits and vegetables can reduce the amount of alkalizing substances required to achieve urinary alkalinization above pH 7.5, making it particularly suitable for the dietary treatment of cystine stone disease. Conclusion Life-long follow-up with dietary modification, hyperhydration, and personalized medical therapy (alkalinization and cystine-binding drugs) are critical in preventing chronic kidney disease and kidney failure in cystinuria.en_US
dc.identifier.doi10.1007/s00345-022-04263-1
dc.identifier.endpage1220en_US
dc.identifier.issn0724-4983
dc.identifier.issn1433-8726
dc.identifier.issue5en_US
dc.identifier.pmid36565321en_US
dc.identifier.scopus2-s2.0-85144865707en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1215en_US
dc.identifier.urihttps://doi.org/10.1007/s00345-022-04263-1
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10903
dc.identifier.volume41en_US
dc.identifier.wosWOS:000903545000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofWorld Journal Of Urologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCystinuriaen_US
dc.subjectCystine Stonesen_US
dc.subjectMedical Treatmenten_US
dc.subjectDiet Managementen_US
dc.subjectDiet In Cystinuriaen_US
dc.subjectAlkalinizationen_US
dc.subjectMedical Therapy In Cystinuriaen_US
dc.subjectSodium Intakeen_US
dc.subjectFluid Intakeen_US
dc.titleCase-based review of dietary management of cystinuriaen_US
dc.typeReview Articleen_US

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