Maternal Antidepressant Use During Pregnancy and the Risk of Attention-Deficit/Hyperactivity Disorder in Children A Systematic Review of the Current Literature

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dc.contributor.authorUguz, Faruk
dc.date.accessioned2024-02-23T14:21:11Z
dc.date.available2024-02-23T14:21:11Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractPurpose: This study reviewed the current literature examining the potential relationship between use of antidepressants during pregnancy and attention-deficit/hyperactivity disorder (ADHD) in children. Methods: PubMed was searched for English language reports between January 1, 1995, and July 31, 2017, by using combinations of the key words pregnancy, antidepressants, selective serotonin reuptake inhibitors (SSRIs), selective serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), children, offspring, and ADHD. Studies that reported association between ADHD in children and use of antidepressant in pregnant women were included in the review. Results: A total of 7 relevant studies that met the review criteria were examined. The studies reported that compared with nonusers adjusted risks of ADHD in children were 1.2 to 1.6 for the use of any antidepressant, 0.91 to 1.66 for selective serotonin reuptake inhibitors, 1.1 to 1.4 for selective serotonin-norepinephrine reuptake inhibitors, and 1.1 to 1.8 for tricyclic antidepressants. There was some scientific evidences suggesting a connection between antidepressant use during all trimesters of pregnancy and increased risk of ADHD in children. In addition, the study results suggest that underlying maternal anxiety or depressive disorders may also contribute to increased risk of ADHD.en_US
dc.identifier.doi10.1097/JCP.0000000000000868
dc.identifier.endpage259en_US
dc.identifier.issn0271-0749
dc.identifier.issn1533-712X
dc.identifier.issue3en_US
dc.identifier.pmid29596147en_US
dc.identifier.scopus2-s2.0-85046104028en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage254en_US
dc.identifier.urihttps://doi.org/10.1097/JCP.0000000000000868
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13480
dc.identifier.volume38en_US
dc.identifier.wosWOS:000431001500017en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Clinical Psychopharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdhden_US
dc.subjectAntidepressantsen_US
dc.subjectPregnancyen_US
dc.titleMaternal Antidepressant Use During Pregnancy and the Risk of Attention-Deficit/Hyperactivity Disorder in Children A Systematic Review of the Current Literatureen_US
dc.typeReview Articleen_US

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