Bullous disorders in Konya: A study of 93 cases

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dc.contributor.authorDaye, Munise
dc.contributor.authorMevlitoglu, Inci
dc.contributor.authorEsener, Sarenur
dc.date.accessioned2024-02-23T14:38:22Z
dc.date.available2024-02-23T14:38:22Z
dc.date.issued2013
dc.departmentNEÜen_US
dc.description.abstractBackground and Design: Bullous diseases are a group of disorders caused by specific antibodies against tissue adhesion molecules in the skin and mucosa or by genetic inheritance. There are limited detailed epidemiological studies about bullous disorders in Turkey. In this study, we evaluated the demographic, clinical and immunopathological findings as well as course of the disease and follow-up properties in patients with bullous disorders in the 'Province of Konya. Materials and Methods: Ninety-three patients, who were followed up between 2006 and 2012, were included in our study: Since most of the patients were in pemphigus and bullous pemphigoid groups, we investigated data on those patients in more detail. Results: 53.8% of patients were female and 46.2% were male. The mean age was 52.9. 37.6% of patients had pemphigus vulgaris, - 34.4% bullous pemphigoid, - 15%hereditary epidermolysis bullosa, - 4.3% dermatitis herpetiformis, - 4.3% pemphigus foliaceus, - 2.2% pemphigus vegetans, - 1.1% Hailey-Hailey disease, and 1.1% of patients had cicatricial pemphigoid. The mean age of onset of pemhigus vulgaris was 45.9 years. Pemhigus vulgaris, which was most frequently observed in females, started at oral mucosa and the time of diagnosis was longer than in patients in the other geographic regions. The mean age of onset of bullous pemphigoid was 70 years and it was mostly observed in females. In 12.5 of cases, the initial manifestations occured the oral mucosa. None of the patients had a concomitant autoimmune disorder. Twenty-five cases were treated with systemic corticosteroids, 41 cases with systemic corticosteroids and adjuvant drugs; 11 patients received only adjuvant therapy, and 16 patients were administered only local steroids. Conclusion: We report the demographical, clinical and immunopathological, findings as well as course of the disease and follow-up properties in patients with bullous disorders in the Province of Konya.en_US
dc.identifier.doi10.4274/turkderm.04810
dc.identifier.endpage204en_US
dc.identifier.issn2717-6398
dc.identifier.issn2651-5164
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84896744736en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage200en_US
dc.identifier.urihttps://doi.org/10.4274/turkderm.04810
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16486
dc.identifier.volume47en_US
dc.identifier.wosWOS:000331341800003en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherDeri Zuhrevi Hastaliklar Dernegien_US
dc.relation.ispartofTurkderm-Turkish Archives Of Dermatology And Venerologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBullous Disordersen_US
dc.subjectPemhigus Vulgarisen_US
dc.subjectBullous Pemphigoiden_US
dc.subjectKonyaen_US
dc.titleBullous disorders in Konya: A study of 93 casesen_US
dc.typeArticleen_US

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