Complete response and long-term remission to anti-HER2 combined therapy in a patient with breast cancer presented with bone marrow metastases

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dc.contributor.authorArtac, Mehmet
dc.contributor.authorKoral, Lokman
dc.contributor.authorToy, Hatice
dc.contributor.authorGuler, Tunc
dc.contributor.authorBoruban, Melih C.
dc.contributor.authorAltundag, Kadri
dc.date.accessioned2024-02-23T14:27:00Z
dc.date.available2024-02-23T14:27:00Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractPresentation with bone marrow metastasis at diagnosis is a rare event in breast carcinoma. Here, we report a rare presentation of metastatic breast cancer patient with bone marrow metastases, who was successfully treated with trastuzumab combined chemotherapy. The regimens initially applied for bone marrow metastasis were docetaxel/adriamycin, gemcitabine/vinorelbine, epirubicin/cyclophosphamide, capecitabine, docetaxel, gemcitabine, and paclitaxel. But, the best response to these regimens was not satisfactory. Our patient was completely treated with etoposide-cisplatin and trastuzumab combination. She is still on remission after five years of metastatic breast cancer diagnosis using letrozole and trastuzumab without complication. Physicians should be careful in treating bone marrow metastases in breast cancer, since patients can show improved marrow function after chemotherapy and long-lasting survival is possible.en_US
dc.identifier.doi10.1177/1078155213480201
dc.identifier.endpage145en_US
dc.identifier.issn1078-1552
dc.identifier.issn1477-092X
dc.identifier.issue2en_US
dc.identifier.pmid23676508en_US
dc.identifier.scopus2-s2.0-84898975135en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage141en_US
dc.identifier.urihttps://doi.org/10.1177/1078155213480201
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14417
dc.identifier.volume20en_US
dc.identifier.wosWOS:000332823400009en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal Of Oncology Pharmacy Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBone Marrow Metastasisen_US
dc.subjectTrastuzumaben_US
dc.subjectMetastatic Breast Canceren_US
dc.titleComplete response and long-term remission to anti-HER2 combined therapy in a patient with breast cancer presented with bone marrow metastasesen_US
dc.typeArticleen_US

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