Immunotherapy era in the treatment of small cell lung cancer

Basit Öğe Kaydı
dc.contributor.authorAraz, Murat
dc.contributor.authorKarakurt Eryilmaz, Melek
dc.date.accessioned2024-02-23T13:59:47Z
dc.date.available2024-02-23T13:59:47Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractSmall cell lung cancer (SCLC) is differentiated from non-small cell lung cancers with its histological and morphological features, rapid response to chemotherapy, and recurrence in a short time after treatment is discontinued. Platinum plus etoposide chemotherapy combination has been used as a standard treatment, and no new drug has been found for more than 30 years in this disease. In research, the targeted pathways that may affect survival have not been identified yet. During the second half of the second decade of the 2000s, with immunotherapies that inhibit immune checkpoints, improvements in survival were achieved for the first time in treating SCLC after many years. Then a rapid increase was observed in chemotherapy plus immunotherapy combination studies in this field. Updated analyses of these studies were represented at international oncology meetings in 2020. Here, we reviewed immunotherapy studies conducted in patients with SCLC and the reflections on the daily practice.en_US
dc.identifier.doi10.1007/s12032-021-01535-5
dc.identifier.issn1357-0560
dc.identifier.issn1559-131X
dc.identifier.issue7en_US
dc.identifier.pmid34156575en_US
dc.identifier.scopus2-s2.0-85109115517en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1007/s12032-021-01535-5
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11323
dc.identifier.volume38en_US
dc.identifier.wosWOS:000664477800001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHumana Press Incen_US
dc.relation.ispartofMedical Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectExtensive Stageen_US
dc.subjectImmunotherapyen_US
dc.subjectLimited Stageen_US
dc.subjectSmall Cell Lung Canceren_US
dc.titleImmunotherapy era in the treatment of small cell lung canceren_US
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu