Diagnostic value of platelet-to-lymphocyte ratio in patients with solitary pulmonary nodules

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dc.contributor.authorKuru, Murat
dc.contributor.authorAltinok, Tamer
dc.date.accessioned2024-02-23T14:41:00Z
dc.date.available2024-02-23T14:41:00Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractIntroduction: Nodules detected in the lung parenchyma should be considered as malignant until proven otherwise, and the necessary tests should be performed for diagnosis.Aim: To calculate the preoperative platelet-to-lymphocyte ratio (PLR) in patients with malignant lung nodules and to investigate the diagnostic value of this ratio in determining the histopathology of the nodule.Material and methods: Ninety-one patients who were operated on for a malignant nodule in the lung between September 2010 and September 2020 were included in the study. The PLR was calculated by dividing the absolute platelet count by the absolute lymphocyte count. These values were compared with the histopathological diagnoses of the resected tumor tissue. Patients with primary lung malignancy were classified as group 1 (n = 54), and lung metastases of other organs were classified as group 2 (n = 37).Results: The mean PLR was 127.27 +/- 46.82 in the first group and 183.56 +/- 93.49 in the second group. There was a statistically significant difference in PLR values between the two groups, and PLR was higher in group 2. There was no statistically significant difference between the two groups in terms of lymph node positivity, nodule size and SuvMax values. A moderately strong, significant and same-sided correlation was observed between nodule size and SuvMax values in the first group of patients (r = 0.48, p = 0.001)Conclusions: PLR values less than 89.41 indicate that the histopathological result may be a lung-derived malignancy. However, in cases where the PLR is detected above 165.6, it would be appropriate to interpret another previously detected malignancy as metastasis to the lung.en_US
dc.identifier.doi10.5114/kitp.2022.119758
dc.identifier.endpage121en_US
dc.identifier.issn1731-5530
dc.identifier.issn1897-4252
dc.identifier.issue3en_US
dc.identifier.pmid36268479en_US
dc.identifier.scopus2-s2.0-85139560038en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage117en_US
dc.identifier.urihttps://doi.org/10.5114/kitp.2022.119758
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16649
dc.identifier.volume19en_US
dc.identifier.wosWOS:000869100600001en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofKardiochirurgia I Torakochirurgia Polska-Polish Journal Of Thoracic And Cardiovascular Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPlateleten_US
dc.subjectLymphocyteen_US
dc.subjectNoduleen_US
dc.subjectLung Canceren_US
dc.subjectMetastasesen_US
dc.titleDiagnostic value of platelet-to-lymphocyte ratio in patients with solitary pulmonary nodulesen_US
dc.typeArticleen_US

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