Risk Factors of Stenotrophomonas maltophilia Blood Stream Infections: Comparison With Other Gram-Negative Blood Stream Infections in Children

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dc.contributor.authorAydin, Zeynep Gokce Gayretli
dc.contributor.authorTanir, Gonul
dc.contributor.authorBayhan, Gulsum Iclal
dc.contributor.authorTeke, Turkan Aydin
dc.contributor.authorAkcan, Ozge Metin
dc.contributor.authorKaman, Ayse
dc.contributor.authorDurmus, Sevgi Yasar
dc.date.accessioned2024-02-23T14:21:10Z
dc.date.available2024-02-23T14:21:10Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractBackground: Stenotrophomonas maltophilia, is a nonfermentative, aerobic, Gram-negative bacilli which is intrinsically resistance to several antibiotics. Treatment options for this bacteria are quite different from the other Gram-negative bacilli, which can represent a therapeutic challenge. To initiate appropriate empiric treatment and to reduce mortality, differentiation of S. maltophilia from other Gram-negative bacteria is critically important. The aim of this study is to distinguish the risk factors of S. maltophilia blood stream infections (BSI) from other Gram-negative BSI. Methods: This was a retrospective, case-control study. Patients with S. maltophilia BSI were selected as cases and patients with non-S. maltophilia Gram-negative BSI were selected as controls. Demographic and clinical characteristics of patients were recorded. Results: Forty-eight cases with S. maltophilia BSI and 144 controls were enrolled in the study. Risk factors for S. maltophilia BSI compared with the control group includes prior use of antibiotics, especially carbapenem, pediatric intensive care unit stay, mechanical ventilator use, indwelling catheters and duration of hospitalization. Conclusions: Breakthrough infection by S. maltophilia can occur in severely ill patients being treated with carbapenem. In the presence of risk factors, to reduce morbidity and mortality, S. maltophilia should be kept in mind when starting empiric treatment.en_US
dc.identifier.doi10.1097/INF.0000000000002800
dc.identifier.endpageE409en_US
dc.identifier.issn0891-3668
dc.identifier.issn1532-0987
dc.identifier.issue12en_US
dc.identifier.pmid33214406en_US
dc.identifier.scopus2-s2.0-85096457559en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpageE406en_US
dc.identifier.urihttps://doi.org/10.1097/INF.0000000000002800
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13466
dc.identifier.volume39en_US
dc.identifier.wosWOS:000588790600004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofPediatric Infectious Disease Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectStenotrophomonas Maltophiliaen_US
dc.subjectBlood Stream Infectionsen_US
dc.subjectChildrenen_US
dc.subjectGram-Negative Bacillien_US
dc.titleRisk Factors of Stenotrophomonas maltophilia Blood Stream Infections: Comparison With Other Gram-Negative Blood Stream Infections in Childrenen_US
dc.typeArticleen_US

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