Investigation of the effect of epicardial adipose tissue thickness on cardiac conduction system in children with type 1 diabetes mellitus

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dc.contributor.authorGuney, Ahmet Yasin
dc.contributor.authorSap, Fatih
dc.contributor.authorEklioglu, Beray Selver
dc.contributor.authorOflaz, Mehmet Burhan
dc.contributor.authorAtabek, Mehmet Emre
dc.contributor.authorBaysal, Tamer
dc.date.accessioned2024-02-23T14:31:52Z
dc.date.available2024-02-23T14:31:52Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractObjectives: Investigation of the association between epicardial adipose tissue thickness (EATT) and P-wave dispersion (Pd), QT dispersion (QTd), corrected QT dispersion (QTcd) and Tp-e interval in children with Type 1 Diabetes Mellitus (T1DM) was aimed. Methods: Forty-one children with T1DM and 41 age- and gender-matched healthy children were included in the study. Demographical characteristics of all cases were examined. In echocardiography; in addition to conventional echocardiographic measurements, end-systolic EATT was measured from right ventricular free wall. In electrocardiogram; Pd, QTd, QTcd and Tp-e interval durations, as well as Tp-e/QT and Tp-e/QTc ratios were calculated. Correlation values between EATT and electrocardiographic parameters were also noted. Results: Mean age of the patient group was determined to be 12.43 +/- 3.04 years and that of the control group was determined to be 12.08 +/- 2.56 years. There was no significant difference between the groups in regard to age, gender, body weight, height and body mass index. In the patient group; EATT, Pd, QTd, QTcd and Tp-e interval were determined to be significantly higher compared to the control group. In the patient group, no significant correlation was determined between EATT and Pd, QTd, QTcd and Tp-e. However, when both patient and control groups were evaluated together, a statistically significant positive correlation was determined between EATT and Pd, QTd, QTcd and Tp-e. Conclusions: In children with T1DM, an increase in epicardial adipose tissue thickness and in risk of cardiac arrhythmias has been demonstrated. To reveal the possible unfavorable effects of EATT on cardiac conduction system in T1DM patients needs further studies.en_US
dc.identifier.doi10.1515/jpem-2020-0001
dc.identifier.endpage720en_US
dc.identifier.issn0334-018X
dc.identifier.issn2191-0251
dc.identifier.issue6en_US
dc.identifier.pmid32441671en_US
dc.identifier.scopus2-s2.0-85086682178en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage713en_US
dc.identifier.urihttps://doi.org/10.1515/jpem-2020-0001
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15387
dc.identifier.volume33en_US
dc.identifier.wosWOS:000541895300004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofJournal Of Pediatric Endocrinology & Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEpicardial Adipose Tissueen_US
dc.subjectP-Wave Dispersionen_US
dc.subjectQt Dispersionen_US
dc.subjectTp-E Intervalen_US
dc.subjectType 1 Diabetes Mellitusen_US
dc.titleInvestigation of the effect of epicardial adipose tissue thickness on cardiac conduction system in children with type 1 diabetes mellitusen_US
dc.typeArticleen_US

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