The Effect of Enteral Nutrition Support Rich in TGF-? in the Treatment of Inflammatory Bowel Disease in Childhood

Basit Öğe Kaydı
dc.contributor.authorAgin, Mehmet
dc.contributor.authorYucel, Aylin
dc.contributor.authorGumus, Meltem
dc.contributor.authorYuksekkaya, Hasan Ali
dc.contributor.authorTumgor, Gokhan
dc.date.accessioned2024-02-23T14:35:14Z
dc.date.available2024-02-23T14:35:14Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractBackground and Objective: Malnutrition is a major complication of inflammatory bowel disease (IBD). Our aim of the study was to examine the effects of Modulen IBD supplementation, which was administered to IBD patients without limiting their daily diet in addition to medical treatment, on the clinical, laboratory, anthropometric values, and disease activities of these patients. Materials and Methods: Seventy three children with IBD were evaluated retrospectively. The cases were classified as those who had Crohn disease receiving (CD-M; n = 16) or not receiving Modulen IBD (CD; n = 19) and those who had ulcerative colitis receiving (UC-M; n = 13) or not receiving Modulen IBD (UC; n = 25). Disease activities, laboratory values, remission rates, and anthropometric measurements of the groups were compared. In addition to IBD treatment, Modulen IBD in which half of the daily calorie requirement was provided was given for eight weeks. Results: In the third month of treatment, 14 (88%) patients were in remission in CD-M group and eight (42%) patients were in remission in CD group. The height and weight z scores, which were low at the time of diagnosis, improved in the first week in CD-M group. Inflammatory parameters (UC) were significantly lower in the UC-M group compared to the UC group in first and third months. In the third month, eight (62%) patients in the UC-M group and four (16%) in the UC group were remitted clinically and in terms of laboratory values. Conclusions: TGF-beta-rich enteral nutrition support in children with IBD is an easy, effective, and reliable approach. It was shown that TGF-beta-rich enteral nutritional supplementation enabled the disease to enter the remission earlier, and contributed to the early recovery of weight and height scores.en_US
dc.identifier.doi10.3390/medicina55100620
dc.identifier.issn1010-660X
dc.identifier.issn1648-9144
dc.identifier.issue10en_US
dc.identifier.pmid31546703en_US
dc.identifier.scopus2-s2.0-85072573485en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3390/medicina55100620
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15941
dc.identifier.volume55en_US
dc.identifier.wosWOS:000503463400012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMedicina-Lithuaniaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPediatricsen_US
dc.subjectGrowth Retardation In Ibden_US
dc.subjectCrohn Diseaseen_US
dc.subjectUlcerative Colitisen_US
dc.subjectModulen Ibden_US
dc.titleThe Effect of Enteral Nutrition Support Rich in TGF-? in the Treatment of Inflammatory Bowel Disease in Childhooden_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu