Cutaneous Vasculitis after Radiotherapy

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dc.contributor.authorTemiz, Selami Aykut
dc.contributor.authorOzer, Ilkay
dc.contributor.authorKanyilmaz, Gul
dc.contributor.authorAtaseven, Arzu
dc.contributor.authorOltulu, Pembe
dc.date.accessioned2024-02-23T14:41:05Z
dc.date.available2024-02-23T14:41:05Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractCutaneous vasculitis is a large heterogeneous group of diseases, where blood vessels are targeted by immunological and inflammatory reactions, which are the primary causes of this condition. Infections, medications, systemic collagenosis, chronic diseases, and malignancies are the secondary factors that cause cutaneous vasculitis. Hemangiomas are the most common primary benign tumors of the spinal cordand are rarely symptomatic. The most commonly manifestedsymptom is pain, but in rare cases, cutaneous vasculitis may lead to paraparesis and paralysis. Radiotherapy (RT) is a safe and effective treatment for symptomatic spinal cord hemangiomas. A 44-year-old male patient was admitted to our dermatology polyclinic with a complaint of a bilateral rash on both legs that had lasted for 1 week. The medical history of the patient included no disease other than a sacral hemangioma with symptomatic pain, for which the patient had been treated with 4500 cGy curative radiotherapy 1 month previously. In our case, it was thought that cutaneous vasculitis was caused by the radiotherapy without any other triggering factor. A skin biopsy was taken to arrive at a definite diagnosis, and in the histopathological examination, abundant amounts of extra-red blood cells and lymphocytes were observed, along with endothelial profiling in superficial vessels; all of which are findings consistent with vasculitis. The patient was diagnosed with cutaneous vasculitis, both clinically and histopathologically. To the best of our knowledge, radiotherapy as a cause of vasculitis has been the subject of very few studies in the literature to date. In this regard, the present report describes a case of cutaneous vasculitis as a possible immune-related side effect of RT.en_US
dc.identifier.doi10.5152/EurJTher.2018.749
dc.identifier.endpage314en_US
dc.identifier.issn2564-7784
dc.identifier.issn2564-7040
dc.identifier.issue4en_US
dc.identifier.startpage312en_US
dc.identifier.urihttps://doi.org/10.5152/EurJTher.2018.749
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16707
dc.identifier.volume25en_US
dc.identifier.wosWOS:000502635500014en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofEuropean Journal Of Therapeuticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCutaneous Vasculitisen_US
dc.subjectHemangiomaen_US
dc.subjectRadioimmunologyen_US
dc.subjectRadiotherapyen_US
dc.titleCutaneous Vasculitis after Radiotherapyen_US
dc.typeArticleen_US

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