Chiral calix[4]arenes bearing ?-hydroxy amide units as membrane carriers for amino acid methyl esters
Küçük Resim Yok
Tarih
2012
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Novel chiral calix[4]arene derivatives functionalized at the lower rim have been prepared from the reaction of p-tert-butylcalix[4]arene diamine or acylhydrazine derivative with mandelic acid or hydroxyisovaleric acid. The structures of these receptors were characterized by FTIR, H-1, C-13 and 2D COSY NMR spectroscopy and elemental analysis. The transport of amino acid derivatives (phenylalanine, phenylglycine and tryptophan methyl ester hydrochlorides) was studied through bulk liquid membrane in the presence of chiral calix[4]arene derivatives. The receptors have been found to act as carriers for transport of aromatic amino acid methylesters from the aqueous source phase to the aqueous receiving phase. The transport rate and L/D selectivity of amino acid esters studied depend strongly upon the structure of the chiral receptors and guests. The best enantioselectivity was obtained in the case of phenylglycine methyl ester for all chiral carriers.
Açıklama
Anahtar Kelimeler
Chiral Calix[4]Arene, Alpha-Hydroxy Amide, Bulk Liquid Membrane, Amino Acid Methyl Esters, Transport Rate
Kaynak
Journal Of Inclusion Phenomena And Macrocyclic Chemistry
WoS Q Değeri
Q2
Scopus Q Değeri
Q3
Cilt
74
Sayı
1.Nis
