Anaphylaxis in older adult patients: a 10-year retrospective experience

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dc.contributor.authorYildiz, Eray
dc.contributor.authorArslan, Sevket
dc.contributor.authorCoelkesen, Fatih
dc.contributor.authorEvcen, Recep
dc.contributor.authorAykan, Filiz Sadi
dc.contributor.authorKilinc, Mehmet
dc.date.accessioned2024-02-23T14:16:29Z
dc.date.available2024-02-23T14:16:29Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractBackground: Despite the worldwide increase in life expectancy and the elderly population, very little is known about the characteristics of anaphylaxis in older adults.Methods: A retrospective scan was made of the files of patients who presented at the Allergy Unit of our clinic between October 2011 and October 2021. The study included 971 patients aged >18 years who met the criteria for diagnosis of anaphylaxis. The patients were separated into 2 groups of adults (18-64 years) and older adults (>65 years).Results: The adult group included 887 (91.3%) patients and the older adult group, 84 (8.7%) patients. Comorbid diseases were seen more frequently in the older adults than in the adult group (p < 0.001). Drugs were seen to be the most common trigger of anaphylaxis in both groups, and this was more common in the older adult group (p = 0.039). Food was a more common trigger of anaphylaxis in the adult group than in the older adult group (p = 0.017). In both groups, the skin was the organ most affected, and was less affected in the older adults than in the adults (p = 0.020). Cardiovascular symptoms were seen significantly more and respiratory symptoms significantly less in the older adult group (p < 0.001, p = 0.002, respectively). Admission to the hospital and the intensive care unit was more frequent in the older adult group and rates of adrenalin administration were higher compared to the adult group (p < 0.001 for all).Conclusion: Anaphylaxis in the older adults is generally caused by drugs. Older adults were found to have more cardiovascular symptoms and more frequent adrenalin injections, hospitalizations and intensive care unit admissions.en_US
dc.identifier.doi10.1016/j.waojou.2022.100665
dc.identifier.issn1939-4551
dc.identifier.issue7en_US
dc.identifier.pmid35891674en_US
dc.identifier.scopus2-s2.0-85134497057en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.waojou.2022.100665
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12671
dc.identifier.volume15en_US
dc.identifier.wosWOS:000830873800001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofWorld Allergy Organization Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnaphylaxisen_US
dc.subjectOlder Adultsen_US
dc.subjectDrug Hypersensitivityen_US
dc.subjectAdrenalineen_US
dc.subjectHospitalizationen_US
dc.titleAnaphylaxis in older adult patients: a 10-year retrospective experienceen_US
dc.typeArticleen_US

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