Cutaneous Mucinosis Case with Characteristic Lion Face Appearance

Basit Öğe Kaydı
dc.contributor.authorTemiz, Selami Aykut
dc.contributor.authorDursun, Recep
dc.contributor.authorAtaseven, Arzu
dc.contributor.authorOzer, Ilkay
dc.contributor.authorFindik, Siddika
dc.date.accessioned2024-02-23T14:41:03Z
dc.date.available2024-02-23T14:41:03Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractCutaneous mucinosis includes a heterogeneous group of skin diseases characterized by the deposition of mucin in the interval of the dermis. Mucin is a protein ordinarily found as part of the dermal connective tissues. Mucin is a mucopolysaccharide produced by mast cells and fibroblasts and includes hyaluronic acid and sulfated glycosaminoglycans. Because hyaluronic acid holds water, in disease states where mucin production is increased, the dermal connective tissue swells, which is defined as myxedematous. Systemic mucin deposition may include systemic involvement; monoclonal gammopathy or paraproteinemia have been detected in the large majority (83.2%) of scleromyxedema cases. A 50-year-old female presented with pruritic, flesh-colored papules spread throughout the body. She also exhibited a characteristic lion face appearance. These lesions had first appeared 18 months before in the neck. The protein electrophoresis and bone marrow biopsy of the patient were normal. Histopathological examination revealed widespread mucin accumulation with alcian blue and colloidal iron stains in the papillary and reticular dermis. Granulomas were not observed with CD68 staining, and no accumulation was observed with amyloid staining. The final diagnosis was cutaneous mucinosis. In this paper we present the case of a patient with generalized primary cutaneous mucinosis without any systemic disease.en_US
dc.identifier.doi10.5152/cjms.2018.527
dc.identifier.endpage119en_US
dc.identifier.issn2149-7893
dc.identifier.issn2536-507X
dc.identifier.issue2en_US
dc.identifier.startpage117en_US
dc.identifier.urihttps://doi.org/10.5152/cjms.2018.527
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16684
dc.identifier.volume3en_US
dc.identifier.wosWOS:000444741800017en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofCyprus Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCutaneous Mucinosisen_US
dc.subjectLion Faceen_US
dc.subjectScleromyxedemaen_US
dc.subjectHydroxychloroquineen_US
dc.titleCutaneous Mucinosis Case with Characteristic Lion Face Appearanceen_US
dc.typeArticleen_US

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