The relationship between FGF23 and anemia in HD and renal transplant patients

Basit Öğe Kaydı
dc.contributor.authorBaloglu, Ismail
dc.contributor.authorOzer, Hakan
dc.contributor.authorOzturk, Yasin
dc.contributor.authorErdur, Mehmet Fatih
dc.contributor.authorTonbul, Halil Zeki
dc.contributor.authorTurkmen, Kultigin
dc.date.accessioned2024-02-23T13:59:28Z
dc.date.available2024-02-23T13:59:28Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractPurpose Recent studies claim that FGF23 is also associated with anemia and inflammation. In this study, the relationship between FGF23 and anemia in hemodialysis (HD) and renal transplantation patients (RTx patients) patients was investigated. Methods This was a cross-sectional study involving 40 RTx patients (13 females, 27 males; mean age, 45.93 +/- 12.49 years) who had transplantation at least 6 months before, 25 HD patients (12 females, 13 males; mean age, 54.72 +/- 15.5 years), and 20 healthy control subjects (13 females, 7 males; mean age, 36.7 +/- 9.38 years). FGF23 was studied using Elisa method. Parameters such as iron, ferritin, total iron binding capacity, and transferrin saturation were assessed. Results FGF23 level was significantly higher in HD patients when compared with the RTx patients and control groups. In the bivariate correlation analysis, hemoglobin was positively correlated with albumin (r = 0.681, p = 0.000), ferritin (r = 0.446, p = 0.043), and negatively correlated with CRP (r = - 0.476, p = 0.016) and FGF23 (r = 0.493, p = 0.043). FGF23 was found to be an independent predictor of decreased hemoglobin in HD patients. In addition, this association was observed to disappear after transplantation. Conclusion While FGF23 is closely related to hemoglobin levels in HD patients, we have shown that this relationship disappears after transplantation.en_US
dc.identifier.doi10.1007/s11255-021-02982-9
dc.identifier.endpage1122en_US
dc.identifier.issn0301-1623
dc.identifier.issn1573-2584
dc.identifier.issue5en_US
dc.identifier.pmid34482498en_US
dc.identifier.scopus2-s2.0-85114173033en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1117en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-021-02982-9
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11210
dc.identifier.volume54en_US
dc.identifier.wosWOS:000693349900001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Urology And Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFgf23en_US
dc.subjectAnemiaen_US
dc.subjectHemodialysisen_US
dc.subjectRenal Transplantationen_US
dc.titleThe relationship between FGF23 and anemia in HD and renal transplant patientsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu