Evaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic Pupillometry

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dc.contributor.authorBitirgen, Gulfidan
dc.contributor.authorDaraghma, Mohammed
dc.contributor.authorOzkagnici, Ahmet
dc.date.accessioned2024-02-23T14:38:20Z
dc.date.available2024-02-23T14:38:20Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractObjectives: To evaluate the pupillary light reflex responses in patients with unilateral strabismic and anisometropic amblyopia using dynamic pupillometry. Materials and Methods: A total of 102 eyes of 51 patients with unilateral amblyopia were included in this cross-sectional study. Of the 51 patients, 37 (72.5%) had strabismic amblyopia and 14 (27.5%) had anisometropic amblyopia. All patients underwent complete ophthalmological examination, and pupillary light reflex responses were measured using a computerized dynamic pupillometry system (MonPack One; Metrovision, France). Initial pupil diameter; the amplitude, latency, duration, and velocity of pupil contraction; and the latency, duration, and velocity of pupil dilation were recorded. Results obtained from the patients' amblyopic and normal fellow eyes were compared using paired-samples t-test and Wilcoxon signed rank test. Results: The mean age of the patients was 11.9 +/- 6.0 years. Amblyopic eyes had longer contraction latency (p=0.009), shorter contraction duration (p=0.002), and higher dilation velocity (p=0.033) compared to fellow eyes, while other parameters did not show significant differences. In subgroup analysis, eyes with strabismic amblyopia had longer contraction latency (p=0.006) and shorter contraction duration (p=0.017), while eyes with anisometropic amblyopia had shorter contraction duration (p=0.030) when compared with fellow eyes. Conclusion: In this study, the objective records obtained by dynamic pupillometry showed that pupillary light reflex responses are affected in amblyopic eyes. This finding may shed light on unclear aspects of the pathophysiology of amblyopia.en_US
dc.identifier.doi10.4274/tjo.galenos.2019.32748
dc.identifier.endpage314en_US
dc.identifier.issn1300-0659
dc.identifier.issn2147-2661
dc.identifier.issue6en_US
dc.identifier.pmid31893585en_US
dc.identifier.scopus2-s2.0-85077388731en_US
dc.identifier.startpage310en_US
dc.identifier.urihttps://doi.org/10.4274/tjo.galenos.2019.32748
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16464
dc.identifier.volume49en_US
dc.identifier.wosWOS:000505067800002en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Ophthalmological Socen_US
dc.relation.ispartofTurk Oftalmoloji Dergisi-Turkish Journal Of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAmblyopiaen_US
dc.subjectAnisometropiaen_US
dc.subjectDynamic Pupillometryen_US
dc.subjectPupillary Light Reflexen_US
dc.subjectStrabismusen_US
dc.titleEvaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic Pupillometryen_US
dc.typeArticleen_US

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