Common Obesity Syndromes in Childhood

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dc.contributor.authorAlbayrak, Hatice Mutlu
dc.contributor.authorEklioglu, Beray Selver
dc.date.accessioned2024-02-23T14:38:09Z
dc.date.available2024-02-23T14:38:09Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractSyndromic obesity occurs with different genetic or chromosomal disorders. Obesity is accompanied by dysmorphic features, mental retardation and developmental abnormalities. Prader-Willi syndrome, Bardet-Biedl syndrome and Alstrom syndrome are the most commonly encountered obesity syndromes, in clinical practice. Prader-Willi syndrome is an obesity syndrome, characterized by hypotonia, hyperphagia, hypogonadism and short stature due to genomic imprinting defect. Bardet-Biedl syndrome is a genetically heterogeneous ciliopathy syndrome caused by autosomal recessive genes, characterized by retinal dystrophy, truncal obesity, postaxial polydactyly, learning difficulties, renal anomalies, and hypogonadotropic hypogonadism only in males, Alstrom syndrome is an autosomal recessive syndrome, characterized by progressive cone-rod dystrophy, obesity and sensorineural hearing loss accompanied by multi-organ involvement. If exogenous and monogenic obesity is excluded, not only hormonal evaluation but also additional dysmorphic features, ophthalmic, dental, cardiac, renal, and neurological systems should also be evaluated to approach syndromic obesity. Genetic diagnostic analysis should be utilized for confirming the diagnosis and providing genetic counseling to families.en_US
dc.identifier.doi10.4274/jcp.85547
dc.identifier.endpage87en_US
dc.identifier.issn1304-9054
dc.identifier.issn1308-6308
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84978757632en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage82en_US
dc.identifier.urihttps://doi.org/10.4274/jcp.85547
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16390
dc.identifier.volume14en_US
dc.identifier.wosWOS:000407729200006en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofGuncel Pediatri-Journal Of Current Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectObesityen_US
dc.subjectGeneticsen_US
dc.subjectPrader-Willi Syndromeen_US
dc.subjectBardet-Biedl Syndromeen_US
dc.subjectAlstrom Syndromeen_US
dc.titleCommon Obesity Syndromes in Childhooden_US
dc.typeReview Articleen_US

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