Monocyte-to-High-Density Lipoprotein Ratio may be Related to the Coronary Artery Disease Reporting and Data System Score and Increased Left Ventricular Mass

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dc.contributor.authorKadiyoran, Cengiz
dc.contributor.authorYilmaz, Pinar Diydem
dc.date.accessioned2024-02-23T14:44:44Z
dc.date.available2024-02-23T14:44:44Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractBackground: Activation of monocytes and lower high-density lipoprotein (HDL) levels accelerate atherosclerosis. The monocyteto-HDL ratio (MHR) and the coronary arterydisease-reporting and data system (CAD-RADS) score are recognized as proper indicators of the atherosclerotic process. Objectives: This study aimed to investigate the relationship between the CAD-RADS score and the left ventricular mass (LVM) and MHR and to evaluate the role of MHR as a predictive marker for the CAD-RADS score. Methods: In this study, the data of 160 patients, who underwent coronary computed tomography angiography (CCTA) for cardiac assessment in our radiology unit between January 2019 and January 2021, were collected and evaluated retrospectively. The CADRADS score, LVM, and MHR were calculated for the patients. Patients and Methods: The multivariate analysis showed independent relationships between CAD-RADS scores and high-sensitive C-reactive protein (hs-CRP) (beta = 407, P < 0.001), MHR (beta = 351, P < 0.001), age (beta = 0.254, P < 0.001), male sex (beta = 0.179, P < 0.001), and diabetes mellitus (beta = 0.122, P = 0.008). The cutoff values of MHR (9.4 for CAD-RADS-1,11.5 for CAD-RADS-2,12.8 for CAD-RADS-3, and 14.0 for CAD-RADS-4) showed high sensitivity and specificity for the CAD-RADS scores. Conclusion: Based on the results, MHR may be associated with the CAD-RADS score and increased LVM. As an inexpensive and reliable test, MHR may be useful for the early diagnosis and follow-up of atherosclerotic heart diseases.en_US
dc.identifier.doi10.5812/iranjradiol.118837
dc.identifier.issn1735-1065
dc.identifier.issn2008-2711
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85125837084en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.urihttps://doi.org/10.5812/iranjradiol.118837
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17089
dc.identifier.volume19en_US
dc.identifier.wosWOS:000786636000009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherBrieflanden_US
dc.relation.ispartofIranian Journal Of Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMonocyte-To-Hdl Ratioen_US
dc.subjectCad-Radsen_US
dc.subjectAtherosclerosisen_US
dc.subjectLeft Ventricular Massen_US
dc.titleMonocyte-to-High-Density Lipoprotein Ratio may be Related to the Coronary Artery Disease Reporting and Data System Score and Increased Left Ventricular Massen_US
dc.typeArticleen_US

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