Evaluation of preemptive dexketoprofen trometamol effect on blood chemistry, vital signs and postoperative pain in dogs undergoing ovariohysterectomy

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dc.contributor.authorSaritas, Z. K.
dc.contributor.authorSaritas, T. B.
dc.contributor.authorPamuk, K.
dc.contributor.authorKorkmaz, M.
dc.contributor.authorYaprakci, M., V
dc.contributor.authorYilmaz, O.
dc.contributor.authorDemirkan, I
dc.date.accessioned2024-02-23T14:37:58Z
dc.date.available2024-02-23T14:37:58Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractObjective: To investigate the postoperative analgesic effects of preemptive dexketoprofen trometamol in dogs subjected to ovariohysterectomy (OHE). Material and methods: Seventeen adult bitches of various breeds were used in this study. The dogs were randomly allocated into of two groups. Subjects in the dexketoprofen trometamol (DEX) group (n=10), received intravenous (i.v.) dexketoprofen trometamol, 1 mg/kg, 15 minutes before premedication, while those assigned to the control (C) group (n=7) were given no analgesics prior to premedication. Pain level was assessed by two researchers before the administration of anaesthesia (15 minutes before start) and 0, 1, 2, 4 and 6 hours after surgery. A modified University of Melbourne Pain Scale (UMPS) was used to evaluate pain in both groups. Results: Serum cortisol level changed from 0 to 1 h and from 0 to 1 to 4 h were compared between the groups; the increase in the C group was statistically significant. The modified UMPS was applied to both groups at baseline and postoperative 1, 2, 4 and 6 h. According to this test, the values for DEX were significantly lower than controls at 4 and 6 h (p<0.001). Conclusion: Stable vital signs with unchanged biochemical parameters on dexketoprofen administration are a promising finding. The clinical advantage shown by the pain scale difference and the low serum cortisol levels should qualify dexketoprofen for preemptive pain management in dogs (Tab. 5, Fig. 2, Ref. 30). Text in PDF wwwelis.sk.en_US
dc.identifier.doi10.4149/BLL_2015_038
dc.identifier.endpage195en_US
dc.identifier.issn0006-9248
dc.identifier.issn1336-0345
dc.identifier.issue3en_US
dc.identifier.pmid25869569en_US
dc.identifier.scopus2-s2.0-84928737197en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage191en_US
dc.identifier.urihttps://doi.org/10.4149/BLL_2015_038
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16314
dc.identifier.volume116en_US
dc.identifier.wosWOS:000351248700011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherComenius Univen_US
dc.relation.ispartofBratislava Medical Journal-Bratislavske Lekarske Listyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDexketoprofen Trometamolen_US
dc.subjectPreemptive Analgesiaen_US
dc.subjectDogen_US
dc.subjectOvariohysterectomyen_US
dc.titleEvaluation of preemptive dexketoprofen trometamol effect on blood chemistry, vital signs and postoperative pain in dogs undergoing ovariohysterectomyen_US
dc.typeArticleen_US

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