Role of varicocele treatment in assisted reproductive technologies

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dc.contributor.authorSonmez, Mehmet G.
dc.contributor.authorHaliloglu, Ahmet H.
dc.date.accessioned2024-02-23T14:02:03Z
dc.date.available2024-02-23T14:02:03Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractObjective: In this review, we investigate the advantage of varicocele repair prior to assisted reproductive technologies (ART) for infertile couples and provide cost analysis information. Materials and methods: We searched the following electronic databases: PubMed, Medline, Excerpta Medica Database (Embase), Cumulative Index to Nursing and Allied Health Literature (CINAHL). The following search strategy was modified for the various databases and search engines: 'varicocele', 'varicocelectomy', 'varicocele repair', 'ART', 'in vitro fertilisation (IVF)', 'intracytoplasmic sperm injection (ICSI)'. Results: A total of 49 articles, including six meta-analyses, 32 systematic reviews, and 11 original articles, were included in the analysis. Bypassing potentially reversible male subfertility factors using ART is currently common practice. However, varicocele may be present in 35% of men with primary infertility and 80% of men with secondary infertility. Varicocele repair has been shown to be an effective treatment for infertile men with clinical varicocele, thus should play an important role in the treatment of such patients due to the foetal/genetic risks and high costs that are associated with increased ART use. Conclusion: Varicocele repair is a cost-effective treatment method that can improve semen parameters, pregnancy rates, and live-birth rates in most infertile men with clinical varicocele. By improving semen parameters and sperm structure, varicocele repair can decrease or even eliminate ART requirement. (C) 2018 Production and hosting by Elsevier B.V. on behalf of Arab Association of Urology.en_US
dc.identifier.doi10.1016/j.aju.2018.01.002
dc.identifier.endpage196en_US
dc.identifier.issn2090-598X
dc.identifier.issn2090-5998
dc.identifier.issue1en_US
dc.identifier.pmid29713550en_US
dc.identifier.scopus2-s2.0-85041182872en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage188en_US
dc.identifier.urihttps://doi.org/10.1016/j.aju.2018.01.002
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11558
dc.identifier.volume16en_US
dc.identifier.wosWOS:000427446800021en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofArab Journal Of Urologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAssisted Reproductive Technologyen_US
dc.subjectIn Vitro Fertilisationen_US
dc.subjectIntracytoplasmic Sperm Injectionen_US
dc.subjectVaricoceleen_US
dc.subjectVaricocelectomyen_US
dc.titleRole of varicocele treatment in assisted reproductive technologiesen_US
dc.typeReview Articleen_US

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