Real data-based optimal control strategies for assessing the impact of the Omicron variant on heart attacks

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dc.contributor.authorEvirgen, Firat
dc.contributor.authorOzkose, Fatma
dc.contributor.authorYavuz, Mehmet
dc.contributor.authorOzdemir, Necati
dc.date.accessioned2024-02-23T14:37:30Z
dc.date.available2024-02-23T14:37:30Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractThis paper presents an investigation into the relationship between heart attacks and the Omicron variant, employing a novel mathematical model. The model incorporates two adjustable control parameters to manage the number of infected individuals and individuals with the Omicron variant. The study examines the model's positivity and boundedness, evaluates the reproduction number (R0), and conducts a sensitivity analysis of the control parameters based on the reproduction number. The model's parameters are estimated using the widely utilized least squares curve fitting method, employing real COVID-19 cases from Tu & BULL;rkiye. Finally, numerical simulations demonstrate the efficacy of the suggested controls in reducing the number of infected individuals and the Omicron population.en_US
dc.description.sponsorshipResearch Fund of the Erciyes University [BAP 211215005]; TUBITAK; Necmettin Erbakan University [BAP 2021-121]; Balikesir University Research Grant; [FDS-2021- 11059]en_US
dc.description.sponsorshipF. OEzkoese was supported by Research Fund of the Erciyes University. Project Number: FDS-2021- 11059.M. Yavuz was supported by TUBITAK and Necmettin Erbakan University Research Grant No. BAP 211215005.N. OEzdemir was supported by Balikesir University Research Grant No. BAP 2021-121.en_US
dc.identifier.doi10.3934/bioeng.2023015
dc.identifier.endpage239en_US
dc.identifier.issn2375-1495
dc.identifier.issue3en_US
dc.identifier.startpage218en_US
dc.identifier.urihttps://doi.org/10.3934/bioeng.2023015
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16133
dc.identifier.volume10en_US
dc.identifier.wosWOS:001058105700001en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAmer Inst Mathematical Sciences-Aimsen_US
dc.relation.ispartofAims Bioengineeringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOmicron Varianten_US
dc.subjectHeart Attacken_US
dc.subjectParameter Estimationen_US
dc.subjectOptimal Controlen_US
dc.subjectSensitivity Analysisen_US
dc.titleReal data-based optimal control strategies for assessing the impact of the Omicron variant on heart attacksen_US
dc.typeArticleen_US

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