Strabismus Surgery in Congenital Fibrosis of the Extraocular Muscles: A Paradigm

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dc.contributor.authorSener, Emin Cumhur
dc.contributor.authorSekeroglu, Hande Taylan
dc.contributor.authorUral, Ozlem
dc.contributor.authorOzturk, Banu Turgut
dc.contributor.authorSanac, Ali Sefik
dc.date.accessioned2024-02-23T14:34:38Z
dc.date.available2024-02-23T14:34:38Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractBackground: Congenital fibrosis of extraocular muscles (CFEOM) is a rare group of disorders with variable phenotypes that result from aberrant innervation to the EOMs leading to synergistic vertical and/or horizontal deviations. We report our experience with the surgical management of patients with CFEOM. Materials and Methods: We reviewed the clinical findings, the surgical management, and outcomes of 52 consecutive CFEOM patients operated by one surgeon at a university hospital setting between 1993 and 2014. Patients were divided into CFEOM1, 2, or 3 based on clinical and/or molecular genetic findings. Results: Thirty-seven (71.2%) cases were bilateral and 15 (28.8%) were unilateral. Six of the bilateral cases had CFEOM2, and the rest of the patients had either CFEOM1 or CFEOM3. The median age at the first surgery was 10 (1-43) years. Twenty-five were females and 27 were males. Nineteen patients had previous strabismus and/or ptosis surgeries elsewhere. The mean number of operations at our center was 1.6 +/- 0.7 (1-4). A temporary stay suture was used in eight patients and permanently in seven. Of the 40 patients with abnormal head position, 18 achieved excellent, 15 good, and seven poor outcomes and ocular alignment in primary position following the latest surgery was excellent in 19, good in 18, and poor in 14 of the patients, as defined in the Methods'' section of the paper. Conclusions: Although patients with CFEOM present significant strabismus surgical challenges because of EOM dysinnervation, fibrosis, and/or heterotopia, satisfactory alignment and improvement of the head posture can be attained in a significant proportion of patients using an individually tailored surgical approach.en_US
dc.identifier.doi10.3109/13816810.2014.973044
dc.identifier.endpage225en_US
dc.identifier.issn1381-6810
dc.identifier.issn1744-5094
dc.identifier.issue4en_US
dc.identifier.pmid25347047en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage208en_US
dc.identifier.urihttps://doi.org/10.3109/13816810.2014.973044
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15683
dc.identifier.volume35en_US
dc.identifier.wosWOS:000345213900002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInforma Healthcareen_US
dc.relation.ispartofOphthalmic Geneticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAberrant Innervationen_US
dc.subjectCongenital Cranial Dysinnervation Disorderen_US
dc.subjectCongenital Fibrosis Extraocular Muscleen_US
dc.subjectStrabismusen_US
dc.subjectStay Sutureen_US
dc.titleStrabismus Surgery in Congenital Fibrosis of the Extraocular Muscles: A Paradigmen_US
dc.typeArticleen_US

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