Childhood interstitial lung disease in Turkey: first data from the national registry

Basit Öğe Kaydı
dc.contributor.authorNayir-Buyuksahin, Halime
dc.contributor.authorEmiralioglu, Nagehan
dc.contributor.authorKilinc, Ayse Ayzit
dc.contributor.authorGirit, Saniye
dc.contributor.authorYalcin, Ebru
dc.contributor.authorEyuboglu, Tugba Sismanlar
dc.contributor.authorCobanoglu, Nazan
dc.date.accessioned2024-02-23T13:43:50Z
dc.date.available2024-02-23T13:43:50Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractThe childhood interstitial lung diseases (chILD) Turkey registry (chILD-TR) was established in November 2021 to increase awareness of disease, and in collaboration with the centers to improve the diagnostic and treatment standards. Here, the first results of the chILD registry system were presented. In this prospective cohort study, data were collected using a data-entry software system. The demographic characteristics, clinical, laboratory, radiologic findings, diagnoses, and treatment characteristics of the patients were evaluated. Clinical characteristics were compared between two main chILD groups ((A) diffuse parenchymal lung diseases (DPLD) disorders manifesting primarily in infancy [group1] and (B) DPLD disorders occurring at all ages [group 2]). There were 416 patients registered from 19 centers. Forty-six patients were excluded due to missing information. The median age of diagnosis of the patients was 6.05 (1.3-11.6) years. Across the study population (n = 370), 81 (21.8%) were in group 1, and 289 (78.1%) were in group 2. The median weight z-score was significantly lower in group 1 (- 2.0 [- 3.36 to - 0.81]) than in group 2 (- 0.80 [- 1.7 to 0.20]) (p < 0.001). When we compared the groups according to chest CT findings, ground-glass opacities were significantly more common in group 1, and nodular opacities, bronchiectasis, mosaic perfusion, and mediastinal lymphadenopathy were significantly more common in group 2. Out of the overall study population, 67.8% were undergoing some form of treatment. The use of oral steroids was significantly higher in group 2 than in group 1 (40.6% vs. 23.3%, respectively; p = 0.040).Conclusion: This study showed that national registry allowed to obtain information about the frequency, types, and treatment methods of chILD in Turkey and helped to see the difficulties in the diagnosis and management of these patients.en_US
dc.description.sponsorshipWe thank all the families and patients for their participation. We thank all the chILD-TR collaborators.en_US
dc.description.sponsorshipWe thank all the families and patients for their participation. We thank all the chILD-TR collaborators.en_US
dc.identifier.doi10.1007/s00431-023-05290-9
dc.identifier.issn0340-6199
dc.identifier.issn1432-1076
dc.identifier.pmid37875631en_US
dc.identifier.scopus2-s2.0-85174639837en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1007/s00431-023-05290-9
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10946
dc.identifier.wosWOS:001091492500001en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Journal Of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInterstitial Lung Diseaseen_US
dc.subjectChildhooden_US
dc.subjectRegistryen_US
dc.titleChildhood interstitial lung disease in Turkey: first data from the national registryen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu