Hemogram parameters in childhood anxiety disorders: Could anxiety disorders be related with inflammation?

Basit Öğe Kaydı
dc.contributor.authorUzun, Necati
dc.contributor.authorAkinci, Mehmet Akif
dc.date.accessioned2024-02-23T14:13:16Z
dc.date.available2024-02-23T14:13:16Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractIn the etiology of anxiety disorders, immune system and inflammation are suggested to play a role. This study hypothesized that there is a relationship between anxiety disorders and inflammation. This retrospective study included 131 children and adolescents between the ages 6-17 who were diagnosed with anxiety disorders. Control group consisted of 131 healthy children with no history of psychiatric disorders or chronic inflammatory conditions. White blood cell (WBC), neutrophil (NEU), lymphocyte, monocyte, basophil, eosinophil values and other hematological markers were noted. From those values, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), monocyte/lymphocyte ratio (MLR), and other ratios were calculated. WBC and NEU values were significantly higher in children and adolescents with anxiety disorder compared to the control group. In addition, NLR, MLR and PLR values were significantly higher than the control group. Other measured parameters and calculated values did not differ between study groups. No statistically significant difference was found between Generalized Anxiety Disorder (GAD) group, Social Anxiety Disorder group and Not Otherwise Specified Anxiety Disorders (AD-NOS) group in terms of hematological markers except RDW-CV. Only RDW-CV was found statistically significantly higher in AD-NOS group compared to GAD. These results show that there is an association between inflammation and anxiety disorders. Also, it is postulated that hematological parameters can be used as a useful marker in the follow-up of patients with anxiety disorders.en_US
dc.identifier.doi10.1016/j.mehy.2020.110440
dc.identifier.issn0306-9877
dc.identifier.issn1532-2777
dc.identifier.pmid33317847en_US
dc.identifier.scopus2-s2.0-85097766721en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.mehy.2020.110440
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12349
dc.identifier.volume146en_US
dc.identifier.wosWOS:000614812300037en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherChurchill Livingstoneen_US
dc.relation.ispartofMedical Hypothesesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnxiety Disordersen_US
dc.subjectInflammationen_US
dc.subjectMonocyte Lymphocyte Ratioen_US
dc.subjectNeutrophil Lymphocyte Ratioen_US
dc.subjectPlatelet Lymphocyte Ratioen_US
dc.titleHemogram parameters in childhood anxiety disorders: Could anxiety disorders be related with inflammation?en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu