Strain and strain rate echocardiography variables in adult Wilson's disease patients: A speckle tracking echocardiography study

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dc.contributor.authorCagan, Suleyman
dc.contributor.authorGurbuz, Ahmet Seyfettin
dc.contributor.authorOzturk, Semi
dc.contributor.authorDemir, Kadir
dc.date.accessioned2024-02-23T12:58:15Z
dc.date.available2024-02-23T12:58:15Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractPurpose Although the hepatic and neurological consequences of Wilson's disease (WD) have been investigated in detail, its cardiac involvement remains little studied. Our aim was to investigate potential cardiac differences in strain (ST) and strain rate (STR) echocardiography in adult WD patients compared with controls. Methods We included 30 patients with WD and a control group of 26 sex and age matched healthy adults. None of the subjects in either group had cardiac complaint. WD patients were clinically evaluated by a neurologist and undergone cranial magnetic resonance imaging. They were then divided into two groups according to the presence (NW) or absence (non-NW) of neurological involvement. Standard and advanced speckle tracking echocardiographic evaluations were performed in each group according to guidelines. Results Left ventricular (LV) systolic and diastolic diameters and wall thickness measurements were within normal limits and did not differ significantly between the groups (P > .05). Neither atrial peak longitudinal and circumferential ST variables nor LV global and longitudinal ST and STR variables showed significant differences between the NW, the non-NW, and the control group (P > .05). Conclusion Our echocardiographic study showed no detectable difference between adult WD patients with or without neurological involvement and healthy subjects.en_US
dc.identifier.doi10.1002/jcu.22849
dc.identifier.endpage329en_US
dc.identifier.issn0091-2751
dc.identifier.issn1097-0096
dc.identifier.issue6en_US
dc.identifier.pmid32374439en_US
dc.identifier.scopus2-s2.0-85085065001en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage324en_US
dc.identifier.urihttps://doi.org/10.1002/jcu.22849
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10616
dc.identifier.volume48en_US
dc.identifier.wosWOS:000530519200001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Clinical Ultrasounden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNervous Systemen_US
dc.subjectSpeckle Tracking Echocardiographyen_US
dc.subjectWilson's Diseaseen_US
dc.titleStrain and strain rate echocardiography variables in adult Wilson's disease patients: A speckle tracking echocardiography studyen_US
dc.typeArticleen_US

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