Sertraline-induced periorbital purpura: a case report

dc.contributor.authorKayhan, Fatih
dc.contributor.authorEken, Zahide Eris
dc.contributor.authorUguz, Faruk
dc.date.accessioned2024-02-23T14:26:59Z
dc.date.available2024-02-23T14:26:59Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractObjective: The incidence of mild to severe levels of spontaneous bleeding due to the usage of selective serotonin reuptake inhibitors (SSRIs) is relatively low. Although the exact mechanism is not known, it is thought that inhibition of the serotonin transporter together with a decrease in platelet serotonin could be responsible for the bleeding. Therefore, the use of SSRIs in conjunction with anti-aggregants may predispose to or exacerbate the risk of bleeding. In this case report, we describe a 44-year-old female patient with a diagnosis of anxiety disorder who spontaneously developed periorbital purpura during treatment with sertraline. Conclusion: Abnormal bleeding after treatment with an SSRI should be kept in mind, and alternative non-SSRI drugs of choice in such cases would be more appropriate. More extensive and comprehensive studies focusing on hemostasis and bleeding disorders are needed for SSRIs such as sertraline.en_US
dc.identifier.doi10.1177/1039856215586138
dc.identifier.endpage428en_US
dc.identifier.issn1039-8562
dc.identifier.issn1440-1665
dc.identifier.issue4en_US
dc.identifier.pmid25964653en_US
dc.identifier.scopus2-s2.0-84947927097en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage426en_US
dc.identifier.urihttps://doi.org/10.1177/1039856215586138
dc.identifier.urihttps://hdl.handle.net/20.500.12452/14410
dc.identifier.volume23en_US
dc.identifier.wosWOS:000358591400024en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofAustralasian Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBleedingen_US
dc.subjectPurpuraen_US
dc.subjectSertralineen_US
dc.subjectSide Effecten_US
dc.titleSertraline-induced periorbital purpura: a case reporten_US
dc.typeArticleen_US

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