A new marker for myocardial injury in carbon monoxide poisoning: T peak-T end

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dc.contributor.authorAkilli, Nazire Belgin
dc.contributor.authorAkinci, Emine
dc.contributor.authorAkilli, Hakan
dc.contributor.authorDundar, Zerrin Defne
dc.contributor.authorKoylu, Ramazan
dc.contributor.authorPolat, Mustafa
dc.contributor.authorCander, Basar
dc.date.accessioned2024-02-23T14:00:18Z
dc.date.available2024-02-23T14:00:18Z
dc.date.issued2013
dc.departmentNEÜen_US
dc.description.abstractObjectives: Carbon monoxide (CO) poisoning frequently affects repolarization, resulting in abnormal electrocardiography findings. The goal of this study was to examine the effect of CO poisoning on the novel transmyocardial repolarization parameters T peak-T end (Tp-e), Tp-e dispersion, and Tp-e/QT and the relationship of these parameters to myocardial injury (MI). Methods: This prospective study included 94 patients with CO poisoning and 40 healthy controls. Participants received an electrocardiography and had their blood drawn at admission and 6 and 24 hours after admission. The QT, Tp-e, Tp-e dispersion, and the Tp-e/QT ratio were calculated. Myocardial injury was determined based on an elevation in troponin any time during the first 24 hours. The patients were divided into 2 subgroups: those with and without MI. Results: T peak-T end, Tp-e dispersion, and the Tp-e/QT ratio were higher at admission than after 6 and 24 hours of hospitalization and were higher than the control group (P < .001). There was a correlation between the carboxyhemoglobin level at admission and Tp-e and Tp-e dispersion (P < .001). The MI subgroup (n = 14) had a higher Tp-e at admission than did the non-MI subgroup (n = 80) (96 [11] milliseconds vs 87 [12] milliseconds, P = .03). There were no any significant differences in the Tp-e dispersion or the Tp-e/QT ratio between the 2 MI subgroups. Receiver operating characteristic analysis showed that a Tp-e cutoff value for MI of 91.5 milliseconds had a sensitivity of 72.7% and a specificity of 67.2%. Conclusion: Transmyocardial repolarization parameters indicative of arrhythmia were prolonged in patients with CO poisoning. T peak-T end was associated with MI. (C) 2013 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajem.2013.08.049
dc.identifier.endpage1655en_US
dc.identifier.issn0735-6757
dc.identifier.issn1532-8171
dc.identifier.issue12en_US
dc.identifier.pmid24091201en_US
dc.identifier.scopus2-s2.0-84889679348en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1651en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajem.2013.08.049
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11544
dc.identifier.volume31en_US
dc.identifier.wosWOS:000327821900005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofAmerican Journal Of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[Keyword Not Available]en_US
dc.titleA new marker for myocardial injury in carbon monoxide poisoning: T peak-T enden_US
dc.typeArticleen_US

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