Green synthesis of silver nanoparticles using Thymbra spicata L. var. spicata (zahter) aqueous leaf extract and evaluation of their morphology-dependent antibacterial and cytotoxic activity

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dc.contributor.authorErci, Fatih
dc.contributor.authorCakir-Koc, Rabia
dc.contributor.authorIsildak, Ibrahim
dc.date.accessioned2024-02-23T14:20:44Z
dc.date.available2024-02-23T14:20:44Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractSilver (Ag) nanoparticles (NPs) were green synthesized at room temperature using different concentrations of the Thymbra spicata L. var. spicata (Zahter) aqueous leaf extracts for the first time. With the synthesis of AgNPs using the leaf extract of Cynara scolymus (Artichoke) and Mentha piperita (Peppermint), the biological activities of the nanoparticles synthesized using leaf extract of three economically significant plants have been studied comparatively. Nanoparticles were characterized by different spectroscopic and microscopic analysis. TEM analysis of the biosynthesized AgNPs revealed that the size and shape of the AgNPs were changed with the plant extract concentration. Biologically synthesized AgNPs from leaf extracts of the three different plants displayed significant differences in antibacterial activity against two different gram-negative and gram-positive bacteria. Also, the results from this study show the shape dependence of the antibacterial and cytotoxic activity of silver nanoparticles synthesized using T. spicata leaf extract. The nanoparticles with different shapes exhibited the strongest antibacterial and cytotoxic activity compared to mostly spherical nanoparticles. Present results clearly indicate that biological activities of silver nanoparticles were affected by nanoparticle shape and the source of the plant extract used in the synthesis.en_US
dc.identifier.doi10.1080/21691401.2017.1415917
dc.identifier.endpageS158en_US
dc.identifier.issn2169-1401
dc.identifier.issn2169-141X
dc.identifier.pmid29250985en_US
dc.identifier.scopus2-s2.0-85038387960en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpageS150en_US
dc.identifier.urihttps://doi.org/10.1080/21691401.2017.1415917
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13281
dc.identifier.volume46en_US
dc.identifier.wosWOS:000457049400013en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofArtificial Cells Nanomedicine And Biotechnologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectThymbra Spicataen_US
dc.subjectGreen Synthesisen_US
dc.subjectSilver Nanoparticlesen_US
dc.subjectAntibacterial Activityen_US
dc.subjectCytotoxicityen_US
dc.titleGreen synthesis of silver nanoparticles using Thymbra spicata L. var. spicata (zahter) aqueous leaf extract and evaluation of their morphology-dependent antibacterial and cytotoxic activityen_US
dc.typeArticleen_US

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