THE COMPARISON OF VITAMIN D LEVELS OF HEALTHY AND GESTATIONAL DIABETIC PREGNANT WOMEN

dc.contributor.authorPekgor, Selma
dc.contributor.authorBasaran, Mustafa
dc.contributor.authorCihan, Fatma Goksin
dc.contributor.authorPekgor, Ahmet
dc.date.accessioned2024-02-23T14:40:45Z
dc.date.available2024-02-23T14:40:45Z
dc.date.issued2017
dc.departmentNEÜen_US
dc.description.abstractAim: To evaluate and compare 25-hydroxyvitamin D [25(OH)D3] levels of women with gestational diabetes mellitus (GDM) and those with normal glucose tolerance (NGT). Material and Method: A total of 40 women (20 with GDM and 20 with NGT) admitted to the clinic of obstetrics and gynecology due to follow-ups between the 24th and 28th gestational weeks and exposed to 50 and/or 100 gr oral glucose tolerance testing (OGTT) were enrolled into this prospective case-controlled study. Patients with GDM and controls with NGT were defined according to the 2013 criteria of the American College of Obstetricians and Gynecologists (ACOG). Age, height, weight, body mass index (BMI), history of previous diseases and surgeries, vitamin D replacement, clothing style (in this region 95% of participants dress in a style that prevents the sun from reaching skin) exercising status, and familial history were recorded. Serum samples were collected between the 24th and 28th gestational weeks to measure 25(OH)D3 levels via the chemiluminescence method. Results: Mean 25(OH)D3 levels were found as 8.71 +/- 3.36 ng/mL (ranging from 4.20 to 18.84). Vitamin D deficiency (< 10 ng/mL) and insufficiency( 10-30 ng/ml) were observed at the rate of 70% and 30%, respectively. 25(OH)D3 levels were 9.40 +/- 3.53ng/mL in patients with GDM and 8.0 +/- 3.11 ng/mL in controls with NGT. In terms of vitamin D deficiency, no statistically significant difference was found between the GDM and NGT groups. Discussion: 25(OH)D3 levels were found to be similar or lower in patients with GDM and those with NGT. We consider that prospective, randomized-controlled and comprehensive studies with larger populations are needed to illuminate the role of 25(OH)D3 levels in the development of GDM.en_US
dc.identifier.doi10.4328/JCAM.4852
dc.identifier.endpage279en_US
dc.identifier.issn1309-0720
dc.identifier.issn1309-2014
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85016607991en_US
dc.identifier.startpage275en_US
dc.identifier.urihttps://doi.org/10.4328/JCAM.4852
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16565
dc.identifier.volume8en_US
dc.identifier.wosWOS:000435654000005en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDerman Medical Publen_US
dc.relation.ispartofJournal Of Clinical And Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGestational Diabetes Mellitusen_US
dc.subjectPregnancyen_US
dc.subjectVitamin D Statusen_US
dc.titleTHE COMPARISON OF VITAMIN D LEVELS OF HEALTHY AND GESTATIONAL DIABETIC PREGNANT WOMENen_US
dc.typeArticleen_US

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