Facile microwave-mediated green synthesis of non-toxic copper nanoparticles using Citrus sinensis aqueous fruit extract and their antibacterial potentials

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dc.contributor.authorJahan, Israt
dc.contributor.authorErci, Fatih
dc.contributor.authorIsildak, Ibrahim
dc.date.accessioned2024-02-23T14:12:45Z
dc.date.available2024-02-23T14:12:45Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractThis study focuses on the utilization of orange (Citrus sinensis) fruit extract for microwave mediated green synthesis of copper nanoparticles for the first time. After completion of the synthesis cycles, the presence of a maximum peak at the wavelength of 560 nm by UV-vis spectroscopy indicated the formation of CuNPs. FTIR spectrum identified the functional biomolecules of the orange juice extract, responsible for the bioreduction, stabilization of copper nanoparticles. Scanning Electron Microscopy (SEM) indicated the presence of globular shaped nano-sized copper particles with smooth surfaces whereas Energy Dispersive X-ray Spectrometry (EDX) confirmed the presence of copper, carbon and oxygen atoms with the amount of 77.68%, 17.55% and 4.77%, respectively. Transmission Electron Microscopy (TEM) illustrated that the CuNPs are morphologically round in shape with the distribution range of 6.93 nm-20.70 nm in diameter. X-ray diffraction (XRD) analysis revealed the presence of face-centered cubic crystalline structures of copper nanoparticle, and Zeta potential analysis confirmed their high stability by showing the strong negative potential value (-25.60 mV). Moreover, these biosynthesized copper nanoparticles displayed their efficiency in controlling the growth of the bacteria, i.e., Escherichia coli and Staphylococcus aureus. The results revealed their non-cytotoxic nature on the L929 mouse fibroblast cell line through XTT cell viability assay. All these studies indicated that CuNPs synthesized by orange extract have the potential to serve as a green nanomaterial for biomedical applications.en_US
dc.identifier.doi10.1016/j.jddst.2020.102172
dc.identifier.issn1773-2247
dc.identifier.issn2588-8943
dc.identifier.scopus2-s2.0-85095794532en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.jddst.2020.102172
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12159
dc.identifier.volume61en_US
dc.identifier.wosWOS:000619157100008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal Of Drug Delivery Science And Technologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCitrus Sinensisen_US
dc.subjectMicrowaveen_US
dc.subjectGreen Synthesisen_US
dc.subjectCopper Nanoparticlesen_US
dc.subjectAntibacterial Activityen_US
dc.subjectCytotoxicityen_US
dc.titleFacile microwave-mediated green synthesis of non-toxic copper nanoparticles using Citrus sinensis aqueous fruit extract and their antibacterial potentialsen_US
dc.typeArticleen_US

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