Modeling the epidemic trend of middle eastern respiratory syndrome coronavirus with optimal control

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dc.contributor.authorFatima, Bibi
dc.contributor.authorYavuz, Mehmet
dc.contributor.authorRahman, Mati Ur
dc.contributor.authorAl-Duais, Fuad S.
dc.date.accessioned2024-02-23T14:37:32Z
dc.date.available2024-02-23T14:37:32Z
dc.date.issued2023
dc.departmentNEÜen_US
dc.description.abstractSince the outbreak of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in 2012 in the Middle East, we have proposed a deterministic theoretical model to understand its transmission between individuals and MERS-CoV reservoirs such as camels. We aim to calculate the basic reproduction number (R0) of the model to examine its airborne transmission. By applying stability theory, we can analyze and visualize the local and global features of the model to determine its stability. We also study the sensitivity of R0 to determine the impact of each parameter on the transmission of the disease. Our model is designed with optimal control in mind to minimize the number of infected individuals while keeping intervention costs low. The model includes time -dependent control variables such as supportive care, the use of surgical masks, government campaigns promoting the importance of masks, and treatment. To support our analytical work, we present numerical simulation results for the proposed model.en_US
dc.description.sponsorshipPrince Sattam bin Abdulaziz University [PSAU/2023/R/1444]en_US
dc.description.sponsorshipAcknowledgement This study is supported via funding from Prince Sattam bin Abdulaziz University project number PSAU/2023/R/1444.en_US
dc.identifier.doi10.3934/mbe.2023527
dc.identifier.endpage11874en_US
dc.identifier.issn1547-1063
dc.identifier.issn1551-0018
dc.identifier.issue7en_US
dc.identifier.pmid37501423en_US
dc.identifier.scopus2-s2.0-85163191723en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage11847en_US
dc.identifier.urihttps://doi.org/10.3934/mbe.2023527
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16146
dc.identifier.volume20en_US
dc.identifier.wosWOS:000993944400002en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAmer Inst Mathematical Sciences-Aimsen_US
dc.relation.ispartofMathematical Biosciences And Engineeringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpidemic Modelen_US
dc.subjectMers-Coven_US
dc.subjectNext Generation Matrix Techniqueen_US
dc.subjectStability Analysisen_US
dc.subjectSensitivity Analysisen_US
dc.subjectOptimal Controlen_US
dc.subjectNumerical Simulationsen_US
dc.titleModeling the epidemic trend of middle eastern respiratory syndrome coronavirus with optimal controlen_US
dc.typeArticleen_US

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