Resveratrol does not affect leptin while it has regulatory effects on liver glycogen levels in exercised and non-exercised rats

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dc.contributor.authorBaltaci, Abdulkerim Kasim
dc.contributor.authorDuran, Mursel Oguzhan
dc.contributor.authorMogulkoc, Rasim
dc.contributor.authorOltulu, Pembe
dc.contributor.authorAvunduk, Mustafa Cihat
dc.date.accessioned2024-02-23T14:16:38Z
dc.date.available2024-02-23T14:16:38Z
dc.date.issued2019
dc.departmentNEÜen_US
dc.description.abstractResveratrol (RES) is a well-known phytocompound and food component which has antioxidative and multifunctional bioactivities. The present study aims to examine how resveratrol administration affects plasma leptin and liver glycogen levels in rats subjected to an acute swimming exercise bout. The study was carried out on Wistar-Albino type adult male rats, each group include 7 rats. Group 1, Control Group. Group 2, Control Swimming Group: The group fed on a standard diet and subjected to an acute swimming exercise bout for 30 minutes at the end of the study. Group 3, Resveratrol Group: The group fed on a standard diet and given (10 mg/kg) resveratrol in drinking water for four weeks. Group 4, Resveratrol + Swimming Group: The group fed on a standard diet, given (10 mg/kg) resveratrol in drinking water for four weeks and subjected to a 30-minute acute swimming exercise at the end of the study. Plasma leptin levels using ELISA method (ng/l) and liver glycogen levels were determined by using histochemical method (number/0.1 mm(2)). Four weeks resveratrol administration to exercised and not-exercised rats did not cause a change in plasma leptin levels. Liver glycogen levels were 17.00 +/- 3.16; 14.12 +/- 2.98; 20.82 +/- 1.97; 16.38 +/- 1.27 (mean +/- sd); respectively in groups 1, 2, 3, 4. Resveratrol administration to rats subjected to a bout of acute swimming exercise produced an effect that prevented the decrease in liver glycogen (p < 0.05). The study highlights that resveratrol supplementation may have regulatory effects on liver glycogen levels in exercised and non-exercised rats.en_US
dc.description.sponsorshipScientific Research Projects Coordinatorship of Selcuk University [14202012]en_US
dc.description.sponsorshipThis study was supported by the Scientific Research Projects Coordinatorship of Selcuk University (SUBAPK; project no. 14202012).en_US
dc.identifier.doi10.1024/0300-9831/a000397
dc.identifier.endpage308en_US
dc.identifier.issn0300-9831
dc.identifier.issn1664-2821
dc.identifier.issue5.Hazen_US
dc.identifier.pmid30932774en_US
dc.identifier.scopus2-s2.0-85075805334en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage303en_US
dc.identifier.urihttps://doi.org/10.1024/0300-9831/a000397
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12744
dc.identifier.volume89en_US
dc.identifier.wosWOS:000498911300010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerlag Hans Huberen_US
dc.relation.ispartofInternational Journal For Vitamin And Nutrition Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSwimming Exerciseen_US
dc.subjectResveratrolen_US
dc.subjectLeptinen_US
dc.subjectGlycogenen_US
dc.subjectRaten_US
dc.titleResveratrol does not affect leptin while it has regulatory effects on liver glycogen levels in exercised and non-exercised ratsen_US
dc.typeArticleen_US

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