Three Parameter Control Algorithm for Obtaining Ideal Postprandial Blood Glucose in Type 1 Diabetes Mellitus

dc.contributor.authorCankaya, Nihat
dc.contributor.authorAydogdu, Omer
dc.date.accessioned2024-02-23T14:23:51Z
dc.date.available2024-02-23T14:23:51Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractThe three main parameters used by patients in diabetes management are initial blood glucose, carbohydrate amount, and mealtime difference. In this study, a novel open-loop control algorithm was proposed, which aims to determine the correct value of mealtime difference duration. Unlike current blood glucose estimation methods, this algorithm was focused on determining extreme points that only concern patients such as hyperglycemia and hypoglycemia, instead of predicting all blood glucose trace in the postprandial period. This new approach has made it possible to determine extreme blood glucose values with simple linear equations without using complex models. This algorithm has only three parameters and has been validated in the UVA Padova type 1 diabetes mellitus simulator, which has thirty in-silico patients. The regressions between real and predicted values for hypoglycemia, hyperglycemia, and mean blood glucose were 0.95, 0.99, and 0.98, respectively. Using the proposed algorithm, the severity of hyperglycemia, mean blood glucose, and standard deviation values were reduced, and hypoglycemia events were prevented. Postprandial blood glucose curves have occurred as desired and within normal limits. Furthermore, it was concluded that intersection points of blood glucose curves contain information about the metabolic parameters of the patients, in this study.en_US
dc.description.sponsorshipBAP Department of Konya Technical University [191102031]en_US
dc.description.sponsorshipThis work was supported in part by the BAP Department of Konya Technical University under Grant 191102031.en_US
dc.identifier.doi10.1109/ACCESS.2020.3015454
dc.identifier.endpage152315en_US
dc.identifier.issn2169-3536
dc.identifier.scopus2-s2.0-85090781221en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage152305en_US
dc.identifier.urihttps://doi.org/10.1109/ACCESS.2020.3015454
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13723
dc.identifier.volume8en_US
dc.identifier.wosWOS:000564231100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherIEEE-Inst Electrical Electronics Engineers Incen_US
dc.relation.ispartofIeee Accessen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInsulinen_US
dc.subjectSugaren_US
dc.subjectBlooden_US
dc.subjectPrediction Algorithmsen_US
dc.subjectMathematical Modelen_US
dc.subjectInsulin Pumpsen_US
dc.subjectSignal Processing Algorithmsen_US
dc.subjectBlood Glucoseen_US
dc.subjectControlen_US
dc.subjectMealtime Differenceen_US
dc.subjectSignal Processingen_US
dc.subjectT1dmen_US
dc.titleThree Parameter Control Algorithm for Obtaining Ideal Postprandial Blood Glucose in Type 1 Diabetes Mellitusen_US
dc.typeArticleen_US

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