Two-Dimensional Shear Wave Elastography in the Assessment of Salivary Gland Involvement in Primary Sjogren's Syndrome

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dc.contributor.authorArslan, Serdar
dc.contributor.authorDurmaz, Mehmet Sedat
dc.contributor.authorErdogan, Hasan
dc.contributor.authorEsmen, Serpil Ergulu
dc.contributor.authorTurgut, Bekir
dc.contributor.authorIyisoy, Mehmet Sinan
dc.date.accessioned2024-02-23T12:20:15Z
dc.date.available2024-02-23T12:20:15Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractObjectives The aim of this study was to investigate the diagnostic performance of two-dimensional (2D) shear wave elastography (SWE) in the assessment of salivary gland involvement in primary Sjogren's syndrome (pSS). Methods Fifty-three patients with pSS and 30 healthy volunteers were included. The echogenicity of all submandibular and parotid glands was evaluated with B-mode ultrasound, and their elasticity was assessed with 2D SWE. The mean and standard deviation of the shear wave speed and elasticity modes on 2D SWE were calculated. Results The mean shear wave speed and elasticity mode values for the submandibular and parotid glands were significantly higher in the patients with pSS (P < .05). The mean elasticity of the shear wave speed mode was best able to differentiate the parotid glands of patients with pSS from those of healthy volunteers at a cutoff value of 2.48 m/s, whereas the mean elasticity of the elasticity mode was best able to differentiate the submandibular glands of patients with pSS from those of healthy volunteers at a cutoff value of 21 kPa. Conclusions Two-dimensional SWE is an effective technique for assessment of the parenchyma of the salivary glands in patients with pSS and predicts interstitial fibrosis and the severity of histologic damage.en_US
dc.identifier.doi10.1002/jum.15179
dc.identifier.endpage956en_US
dc.identifier.issn0278-4297
dc.identifier.issn1550-9613
dc.identifier.issue5en_US
dc.identifier.pmid31763717en_US
dc.identifier.scopus2-s2.0-85082667590en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage949en_US
dc.identifier.urihttps://doi.org/10.1002/jum.15179
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10601
dc.identifier.volume39en_US
dc.identifier.wosWOS:000498295700001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Ultrasound In Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSalivary Glandsen_US
dc.subjectShear Wave Elastographyen_US
dc.subjectSjogren's Syndromeen_US
dc.subjectUltrasounden_US
dc.titleTwo-Dimensional Shear Wave Elastography in the Assessment of Salivary Gland Involvement in Primary Sjogren's Syndromeen_US
dc.typeArticleen_US

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