COMPARISON OF CARDIAC ARRHYTHMIA TYPES BETWEEN HYPERTHYROID PATIENTS WITH GRAVES' DISEASE AND TOXIC NODULAR GOITER

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dc.contributor.authorTuran, E.
dc.contributor.authorCan, I.
dc.contributor.authorTuran, Y.
dc.contributor.authorUyar, M.
dc.contributor.authorCakir, M.
dc.date.accessioned2024-02-23T14:38:01Z
dc.date.available2024-02-23T14:38:01Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractPurpose. Previous studies have demonstrated the relationship between hyperthyroidism and increased risk of cardiac arrhythmias. The most common causes of hyperthyroidism are Graves' disease (GD) and toxic nodular goiter (TNG). The aim of our study was to demonstrate if the underlying mechanism of hyperthyroidism, in other words autoimmunity, has an impact on the type of cardiac arrhythmias accompanying hyperthyroidism. Method. Twenty patients with TNG and 16 patients with GD who had overt hyperthyroidism were included in the study. Age, sex, thyroid hormone levels, thyroid autoantibody positivity, thyroid ultrasonography and scintigraphy results were recorded. 24-hour Holter ECG monitoring was performed in all patients. Results. Mean age was significantly higher in the TNG group compared to the GD group (62.9 +/- 11.5 vs. 48.9 +/- 8.6 years, p=0.001). Free T3 was significantly higher (7.87 +/- 3.90 vs. 5.21 +/- 1.53 pg/mL, p=0.033) in the GD group while free T4 and TSH levels were similar between the two groups. In 24-hour Holter ECG recordings nonsustained ventricular tachycardia (VT) rates were significantly higher in the GD group than in TNG group [18.75% (n=3/16) vs. 0% (n=0/20), respectively, (p=0.043)] Paroxysmal atrial fibrillation (AF) rates were significantly higher in the TNG group compared to GD group [(30% (n=6/20) vs. 0% (n=0/16), respectively, (p=0.016)]. Conclusion. Although free T3 levels were lower, paroxysmal AF rates were found significantly higher in the TNG group which may be associated with significantly higher age of this group. On the other hand, higher rate of nonsustained VT in the GD group may be related to either significantly higher free T3 levels or autoimmunity.en_US
dc.identifier.doi10.4183/aeb.2018.324
dc.identifier.endpage329en_US
dc.identifier.issn1841-0987
dc.identifier.issn1843-066X
dc.identifier.issue3en_US
dc.identifier.pmid31149279en_US
dc.identifier.scopus2-s2.0-85056382863en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage324en_US
dc.identifier.urihttps://doi.org/10.4183/aeb.2018.324
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16333
dc.identifier.volume14en_US
dc.identifier.wosWOS:000451246700007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEditura Acad Romaneen_US
dc.relation.ispartofActa Endocrinologica-Bucharesten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHyperthyroidismen_US
dc.subjectArrhythmiaen_US
dc.subjectEcg Monitoringen_US
dc.subjectGraves' Diseaseen_US
dc.subjectToxic Nodular Goiteren_US
dc.titleCOMPARISON OF CARDIAC ARRHYTHMIA TYPES BETWEEN HYPERTHYROID PATIENTS WITH GRAVES' DISEASE AND TOXIC NODULAR GOITERen_US
dc.typeArticleen_US

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