Orexin a levels of adolescents with major depressive disorder

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dc.contributor.authorAkca, O. F.
dc.contributor.authorSaglam, E.
dc.contributor.authorKilinc, I
dc.contributor.authorBilgic, A.
dc.date.accessioned2024-02-23T14:20:33Z
dc.date.available2024-02-23T14:20:33Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractObjective This study examines orexin A levels in adolescents with major depressive disorder (MDD). Methods Serum orexin A levels of adolescents with MDD (n = 40) were compared to healthy controls (n = 38) using ANCOVA test. In addition, the relationship between orexin A levels and MDD symptom severity (i.e., child depression inventory) was investigated in the MDD group using correlation and linear regression analyses. Results Orexin A levels of the subjects with MDD were similar to controls while controlling for age, gender, body mass index, and anxiety levels of the subjects. In addition, correlation and regression analyses did not reveal any relationship between orexin A and MDD symptoms. Discussion Adolescent MDD is not associated with orexin A according to the findings of this study. Future studies considering the effect of stress on this relationship would improve our understanding of this issue.en_US
dc.identifier.doi10.1080/13651501.2021.1927106
dc.identifier.endpage406en_US
dc.identifier.issn1365-1501
dc.identifier.issn1471-1788
dc.identifier.issue4en_US
dc.identifier.pmid34032542en_US
dc.identifier.scopus2-s2.0-85106439329en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage403en_US
dc.identifier.urihttps://doi.org/10.1080/13651501.2021.1927106
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13212
dc.identifier.volume25en_US
dc.identifier.wosWOS:000654058500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofInternational Journal Of Psychiatry In Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOrexinen_US
dc.subjectDepressionen_US
dc.subjectAnxietyen_US
dc.subjectAdolescenten_US
dc.subjectHypocretinen_US
dc.titleOrexin a levels of adolescents with major depressive disorderen_US
dc.typeArticleen_US

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