Mean Platelet Volume and Neutrophil-to-Lymphocyte Ratio May Be Used as Predictors in Febrile Seizures

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dc.contributor.authorYazar, Abdullah
dc.contributor.authorAkin, Fatih
dc.contributor.authorTure, Esra
dc.contributor.authorCaksen, Huseyin
dc.contributor.authorOdabas, Dursun
dc.date.accessioned2024-02-23T14:16:53Z
dc.date.available2024-02-23T14:16:53Z
dc.date.issued2018
dc.departmentNEÜen_US
dc.description.abstractFebrile seizure (FS) is the most frequent seizure disorder in childhood, associated with rapid onset of high fever. Our study aims are (1) to determine if the levels of mean platelet volume (MPV) and neutrophil-to-lymphocyte ratio (NLR) are risk factors for FS and to (2) assess the usefulness of these markers as predictors to distinguish the subgroups of FS. This prospective study includes children with FS, acute febrile illness (AFI) without seizure, and control group. Complete blood count was performed on all participants. The following data were obtained: white blood cell count (WBC), platelet count, MPV, hemoglobin (Hb), absolute neutrophil count (ANC), absolute lymphocyte count (ALC), and NLR. MPV, WBC, ANC, and NLR were significantly increased in patients with AFI and FS compared with controls (p < 0.05). When patients with FS and AFI were compared, only WBC was increased significantly in patients with FS (p < 0.05). WBC, ANC, and NLR were significantly increased in patients with complex FS compared with simple (p < 0.05). Our findings showed that WBC, MPV, ANC, and NLR were higher in children with FS than in the control group. Additionally WBC, ANC, and NLR were found to be higher in children with CFS than in those with simple febrile seizure. Based on the study results, we suggest that only WBC may be used as predictors in children with FS.en_US
dc.identifier.doi10.1055/s-0038-1668534
dc.identifier.endpage286en_US
dc.identifier.issn1305-7707
dc.identifier.issn1305-7693
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85056092524en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage283en_US
dc.identifier.urihttps://doi.org/10.1055/s-0038-1668534
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12848
dc.identifier.volume13en_US
dc.identifier.wosWOS:000449161500005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofJournal Of Pediatric Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFebrile Seizureen_US
dc.subjectNeutrophil-To-Lymphocyte Ratioen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectChildrenen_US
dc.titleMean Platelet Volume and Neutrophil-to-Lymphocyte Ratio May Be Used as Predictors in Febrile Seizuresen_US
dc.typeArticleen_US

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