Antioxidant and Anti-Atherogenic Properties of Hawthorn Vinegar in Drosophila melanogaster Fed a High-Fat Diet

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dc.contributor.authorSayin, Kubra
dc.contributor.authorGunes, Eda
dc.date.accessioned2024-02-23T14:35:24Z
dc.date.available2024-02-23T14:35:24Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractConsumption of vinegar has been associated with protection against hyperglycemia, dyslipidemia, and hypertension. Hawthorn is a medicinal plant with hypolipidemic, anti-inflammatory, digestive modulator, antimicrobial, antioxidant, cardiac stimulant, and hypotensive properties. Therefore, Hawthorn vinegar rich in bioactives (epicatechin, triterpene, saponins, oligomeric procyanidins, chlorogenic acid, and flavonoids) may present a greater value as a functional food for the management of lifestyle diseases. Drosophila melanogaster, when placed on a high-fat diet, exhibit decreased life span and increased antioxidant enzymes. In this high-fat diet fly model, the Hawthorn vinegar led to a significant increase in mean life span, antioxidant enzyme activities, and reduction in malonyldialdehyde level. Furthermore, in vitro studies showed inhibition of alpha-glucosidase and alpha-amylase, and angiotensin-converting enzyme II activities, the measures of antiglycemic and antihypertensive potentials, respectively.en_US
dc.description.sponsorshipNecmettin Erbakan University Scientific Research Project Coordination [171230004]en_US
dc.description.sponsorshipThis research is supported by the Necmettin Erbakan University Scientific Research Project Coordination by the Project No. 171230004.en_US
dc.identifier.doi10.37290/ctnr2641-452X.20:84-89
dc.identifier.endpage89en_US
dc.identifier.issn1540-7535
dc.identifier.issn2641-452X
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85126909820en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage84en_US
dc.identifier.urihttps://doi.org/10.37290/ctnr2641-452X.20:84-89
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16015
dc.identifier.volume20en_US
dc.identifier.wosWOS:000748366700011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherNew Century Health Publishers, Llcen_US
dc.relation.ispartofCurrent Topics In Nutraceutical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAngiotensin-Converting Enzymeen_US
dc.subjectAnti-Atherogenic Activityen_US
dc.subjectAntioxidant Activityen_US
dc.subjectDrosophila Melanogasteren_US
dc.subjectHawthorn Vinegaren_US
dc.titleAntioxidant and Anti-Atherogenic Properties of Hawthorn Vinegar in Drosophila melanogaster Fed a High-Fat Dieten_US
dc.typeArticleen_US

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