Evaluation of epicardial adipose tissue, carotid intima-media thickness and ventricular functions in obese children and adolescents

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dc.contributor.authorAlp, Hayrullah
dc.contributor.authorEklioglu, Beray Selver
dc.contributor.authorAtabek, Mehmet Emre
dc.contributor.authorKaraarslan, Sevim
dc.contributor.authorBaysal, Tamer
dc.contributor.authorAltin, Hakan
dc.contributor.authorKaratas, Zehra
dc.date.accessioned2024-02-23T14:31:52Z
dc.date.available2024-02-23T14:31:52Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractBackground: Childhood obesity is a cardiovascular risk factor. Objective: Epicardial adipose tissue (EAT) thickness, carotid intima-media thickness (IMT) and cardiac functions of obese children and their correlations were evaluated. Subjects: Five hundred obese children and 150 age-and sex-matched healthy controls. Methods: Anthropometric, laboratory data and echocardiographic measurements of IMT, EAT and cardiac functions were determined. Results: Increased M-mode echocardiographic measurements, E/e' ratios, Tei index values and decreased E/A and e'/a' ratios (where E and A are early and late mitral/tricuspid diastolic velocities, respectively, and e' and a' are peak early diastolic and peak atrial systolic myocardial velocities, respectively), were determined in the obese group. Also, carotid artery IMT and EAT thickness were significantly higher in obese children. Carotid artery IMT, EAT thickness and left ventricular mass (LVM) were found to be strongly associated with Tei index values. Conclusion: Obesity is a major risk factor for cardiovascular diseases. In our study, we showed that obese children have early subclinical systolic and diastolic dysfunctions. Also, these cardiac impairments are correlated with the increase in IMT, EAT thickness and LVM.en_US
dc.identifier.doi10.1515/jpem-2013-0306
dc.identifier.endpage835en_US
dc.identifier.issn0334-018X
dc.identifier.issn2191-0251
dc.identifier.issue9.Ekien_US
dc.identifier.pmid24756043en_US
dc.identifier.scopus2-s2.0-84906968713en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage827en_US
dc.identifier.urihttps://doi.org/10.1515/jpem-2013-0306
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15382
dc.identifier.volume27en_US
dc.identifier.wosWOS:000341429100005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofJournal Of Pediatric Endocrinology & Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiac Functionsen_US
dc.subjectChildrenen_US
dc.subjectEpicardial Adipose Tissueen_US
dc.subjectIntima-Media Thicknessen_US
dc.subjectObesity, Subclinical Cardiac Dysfunctionen_US
dc.titleEvaluation of epicardial adipose tissue, carotid intima-media thickness and ventricular functions in obese children and adolescentsen_US
dc.typeArticleen_US

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