TAFI gene polymorphisms in patients with cerebral venous thrombosis

Küçük Resim Yok

Tarih

2013

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer Heidelberg

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Gene polymorphisms of thrombin activatable fibrinolysis inhibition (TAFI) factor have been investigated in various studies in terms of etiology (recurrence) and treatment (fibrinolytic effect) of thrombus formation. Cerebral venous thrombosis (CVT) is a life-threatening disease observed in young persons. Fifty-nine patients with CVT and 100 healthy control subjects were enrolled in the case/control study. The association between TAFI gene polymorphisms -438G > A, +505A > G and +1040C > T and cerebral venous thrombosis was investigated. It was found that frequencies of polymorphic genotype and allele were not different in patients than in control group and that they were not significant for cerebral venous thrombosis.

Açıklama

Anahtar Kelimeler

Tafi, Cerebral Venous Thrombosis, 438g > A, 505a > G, 1040c > T, Sinus Thrombosis

Kaynak

Acta Neurologica Belgica

WoS Q Değeri

Q4

Scopus Q Değeri

Q2

Cilt

113

Sayı

3

Künye