Suicidal behavior in treatment resistant major depressive disorder patients treated with transmagnetic stimulation(TMS) and its relationship with cognitive functions

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dc.contributor.authorOzcan, Selma
dc.contributor.authorGica, Sakir
dc.contributor.authorGulec, Huseyin
dc.date.accessioned2024-02-23T14:13:39Z
dc.date.available2024-02-23T14:13:39Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractThe aim of this study is to investigate the effects of rTMS treatment on suicidal thoughts/behaviors and to determine the cognitive mechanisms underlying the effects of rTMS treatment on suicidal thoughts/behaviors in treatment-resistant depression(TRD). Thirty patients with TRD received rTMS 5 sessions per week for 4-6 weeks. Montgomery-Asberg Depression Rating Scale(MADRS), Columbia Suicide Severity Rating Scale(C-SSRS), Suicidal Ideation Scale(SIS), Beck Hopelessness Scale(BHS) and Cambridge Neuropsychological Test Automated Battery(CANTAB) were administered before and after treatment. After rTMS treatment, there was a significant decrease in depressive complaints and suicidal thoughts and improvement in emotional recognition. However, there was no significant change in cognitive functions such as cognitive flexibility, motor response inhibition and decision making. Pre-treatment decision-making and flexible thinking skills were related to the change in suicidal ideation. In TRD patients, rTMS has a positive effect on depressive symptoms and suicidal thoughts/behaviors and emotion recognition abilities. Although there is no negative effect on other cognitive functions, the positive effect of rTMS on cognitive functions is limited. At this point, we think that the TRD would be treated more effectively with treatments targeting specific symptom clusters such as other cognitive functions and suicidal thoughts.en_US
dc.identifier.doi10.1016/j.psychres.2020.112873
dc.identifier.issn0165-1781
dc.identifier.issn1872-7123
dc.identifier.pmid32114209en_US
dc.identifier.scopus2-s2.0-85079844075en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.psychres.2020.112873
dc.identifier.urihttps://hdl.handle.net/20.500.12452/12518
dc.identifier.volume286en_US
dc.identifier.wosWOS:000525300400038en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofPsychiatry Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTreatment Resistant Depressionen_US
dc.subjectTranscranial Magnetic Stimulationen_US
dc.subjectSuicideen_US
dc.subjectEmotion Recognitionen_US
dc.subjectDecision-Makingen_US
dc.subjectCognitive Flexibilityen_US
dc.subjectResponse Inhibitionen_US
dc.titleSuicidal behavior in treatment resistant major depressive disorder patients treated with transmagnetic stimulation(TMS) and its relationship with cognitive functionsen_US
dc.typeArticleen_US

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