The effect of etanercept on a case of amyloidosis secondary to ankylosing spondylitis: results of 2-year follow-up

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dc.contributor.authorYilmaz, Halim
dc.contributor.authorKocabas, Hilal
dc.contributor.authorErkin, Gulten
dc.date.accessioned2024-02-23T14:45:45Z
dc.date.available2024-02-23T14:45:45Z
dc.date.issued2013
dc.departmentNEÜen_US
dc.description.abstractSecondary amyloidosis (type AA) is rarely encountered but can be a significant complication of ankylosing spondylitis (AS) and may lead to proteinuria and renal dysfunction. Anti-tumor necrosis factor-alpha (anti-TNF-alpha) agents may be used to induce clinical remission by suppressing systemic inflammation in secondary amyloidosis. The patient described, with the diagnosis of AS, was diagnosed with secondary amyloidosis, despite treatment with disease modifying anti-rheumatic medication. He developed marked proteinuria, renal dysfunction and low levels of serum albumin. Diagnosis of amyloidosis was confirmed by renal biopsy During a 2-year treatment period with etanercept, an anti-TNF-alpha agent, a definite improvement was determined in all parameters. This case illustrates that in the treatment of secondary amyloidosis related to AS, etanercept, an anti-TNF-alpha agent, can be considered an effective therapeutic option.en_US
dc.identifier.endpage301en_US
dc.identifier.issn0303-464X
dc.identifier.issue4en_US
dc.identifier.pmid24435036en_US
dc.identifier.scopus2-s2.0-84893463170en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage299en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12452/17602
dc.identifier.volume38en_US
dc.identifier.wosWOS:000330915500011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPublisaude-Edicoes Medicas Ldaen_US
dc.relation.ispartofActa Reumatologica Portuguesaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing Spondylitisen_US
dc.subjectSecondary Amyloidosisen_US
dc.subjectEtanercepten_US
dc.subjectRenal Functionen_US
dc.titleThe effect of etanercept on a case of amyloidosis secondary to ankylosing spondylitis: results of 2-year follow-upen_US
dc.typeArticleen_US

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