Evaluation of depression and quality of life in patients with obstructive sleep apnea syndrome

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dc.contributor.authorYosunkaya, S.
dc.contributor.authorKutlu, R.
dc.contributor.authorCihan, F. G.
dc.date.accessioned2024-02-23T14:37:45Z
dc.date.available2024-02-23T14:37:45Z
dc.date.issued2016
dc.departmentNEÜen_US
dc.description.abstractBackground: Sleep fragmentation, repetitive hypoxemia during sleep, excessive sleepiness during the day, lack of concentration, memory loss, depression, decreased libido, and impotence are the characteristics of obstructive sleep apnea syndrome (OSAS) that may impair quality of life (QOL). This study aimed to investigate the QOL and factors that may affect QOL in people with different OSAS severity and without sleep apnea. Methods: This was an analytical cross-sectional study. Polysomnography was performed on 200 people. Those detected as having nonapnea and mild-moderate-severe OSAS were administered the Epworth sleepiness scale, Beck Depression Inventory, and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) scale. Results: According to the apnea-hypopnea index, 36 people (18.0%) were in the nonapnea-hypopnea group, 28 (14.0%) in the mild OSAS group, 63 (31.5%) in the moderate OSAS group, and 73 people (36.5%) were in the severe OSAS group. Depression was present in 31 people (15.5%) who participated in the study. The nonapnea-hypopnea group comprised 12.9% of those with depression, mild OSAS group comprised 16.1%, moderate OSAS group comprised 22.6%, and severe OSAS group had 48.4% of the depressed subjects. Beck depression scores showed a significant positive correlation with the Epworth scale (t 90% SaO2) (r = 0.285, P 0.001 and r = 0.283, P 0.001, respectively). The mean scores of WHOQOL-BREF subgroups' physical health (P 0.001), psychological health (P 0.001), social relations (P 0.001), and the environmental area (P 0.001) in those with depression were statistically significantly lower than those without depression. QOL was significantly associated with the presence of OSAS (P = 0.008). Conclusion: Decreased deep sleep duration, increased arousal index, and a high ratio of sleep duration with oxygen saturation below 90% to the duration of the entire sleep period increase daytime sleepiness and depressive symptoms in those with OSAS; thus, disrupting general health and QOL.en_US
dc.identifier.doi10.4103/1119-3077.188703
dc.identifier.endpage579en_US
dc.identifier.issn1119-3077
dc.identifier.issue5en_US
dc.identifier.pmid27538542en_US
dc.identifier.scopus2-s2.0-84983604568en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage573en_US
dc.identifier.urihttps://doi.org/10.4103/1119-3077.188703
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16228
dc.identifier.volume19en_US
dc.identifier.wosWOS:000383807300001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofNigerian Journal Of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDepressionen_US
dc.subjectObstructive Sleep Apneaen_US
dc.subjectQuality Of Lifeen_US
dc.titleEvaluation of depression and quality of life in patients with obstructive sleep apnea syndromeen_US
dc.typeArticleen_US

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