Effects of intranasal mometasone furoate on blood pressure in patients with allergic rhinitis

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dc.contributor.authorKartal, O.
dc.contributor.authorBaysan, O.
dc.contributor.authorGulec, M.
dc.contributor.authorCaliskaner, A. Z.
dc.contributor.authorSener, O.
dc.contributor.authorKaraayvaz, M.
dc.date.accessioned2024-02-23T14:41:32Z
dc.date.available2024-02-23T14:41:32Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractBackground: Nasal congestion as the main symptom in patients with allergic rhinitis can impair nasal breathing. It causes hypoxia and concomitant sympathetic system activation which may also lead to increased blood pressure levels in these patients. Objective: We postulated that appropriate therapy including intranasal steroids decreases blood pressure levels in patients with allergic rhinitis. Methods: In our study, we investigated the effect of intranasal steroid (4 weeks of mometasone furoate) on blood pressure changes in 45 patients with allergic rhinitis whose main complaint was nasal congestion. We used ambulatory monitoring for determining blood pressure levels before and after intranasal steroid therapy. None of the patients had any other systemic diseases. Results: We found a significant decrease of daytime systolic and diastolic blood pressures and mean blood pressure values (daytime systolic blood pressure: 120 vs. 117 mmHg, p = 0.024; daytime diastolic blood pressure: 73 vs. 71 mmHg, p = 0.027; daytime mean blood pressure: 86 vs. 83 mmHg, p = 0.007.). Although insignificant, we also found lower nighttime systolic and mean blood pressure values (nighttime systolic blood pressure: 109 vs. 107 mmHg, p = 0.182; nighttime mean blood pressure 77 vs. 73 mmHg, p = 0.116). Conclusions: We found that post-treatment daytime average systolic, diastolic, and mean arterial blood pressure levels were significantly lower compared to values obtained during exacerbation of allergic rhinitis. Decrease in blood pressure with treatment of allergic rhinitis and nasal congestion suggests that nasal congestion and impaired nasal respiration may affect blood pressure and potentially cause serious problems in hypertensive patients with allergic rhinitis.en_US
dc.identifier.doi10.5414/ALX01764
dc.identifier.endpage477en_US
dc.identifier.issn0344-5062
dc.identifier.issue9en_US
dc.identifier.scopus2-s2.0-84943738672en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage471en_US
dc.identifier.urihttps://doi.org/10.5414/ALX01764
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16886
dc.identifier.volume38en_US
dc.identifier.wosWOS:000361927900003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isodeen_US
dc.publisherDustri-Verlag Dr Karl Feistleen_US
dc.relation.ispartofAllergologieen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAllergic Rhinitisen_US
dc.subjectBlood Pressureen_US
dc.subjectNasal Steroiden_US
dc.subjectMometasone Furaoateen_US
dc.subjectNasal Congestionen_US
dc.titleEffects of intranasal mometasone furoate on blood pressure in patients with allergic rhinitisen_US
dc.typeArticleen_US

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